Men’s Health: The Best Supplements for Managing Prostate Enlargement

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Prostate enlargement, medically known as benign prostatic hyperplasia (BPH), affects many men as they age, leading to discomfort and a variety of urinary symptoms. While conventional treatments are effective, nutritional supplements offer a complementary approach to support prostate health and manage symptoms. This article explores the potential benefits of specific nutritional supplements in addressing prostate enlargement. From natural herb extracts to essential nutrients, we delve into how these supplements can contribute to prostate wellness, potentially easing symptoms and improving quality of life for those dealing with BPH.

What Is Benign Prostatic Hypertrophy (BPH)?

Benign Prostatic Hypertrophy (BPH), also known as benign prostatic hyperplasia, is a common condition in men, especially as they age. It involves the non-cancerous enlargement of the prostate gland, which is located below the bladder and surrounds the urethra, the tube through which urine passes out of the body.

As the prostate enlarges, it can press against the urethra and bladder, leading to urinary symptoms such as increased frequency of urination, nocturia (needing to urinate frequently during the night), difficulty starting urination, a weak urine stream, and the feeling of incomplete bladder emptying.

BPH does not increase the risk of prostate cancer, but its symptoms can significantly affect a man’s quality of life. The exact cause of BPH is not fully understood, but it is believed to be related to changes in hormone levels as men age.

What Food and Lifestyle Factors Are Important For Managing Prostate Enlargement?

Managing prostate enlargement, also known as benign prostatic hyperplasia (BPH), involves a combination of medical treatment, diet, and lifestyle modifications. Here are some food and lifestyle factors that can play a crucial role in managing the condition:

Food and Nutrition:

  • Increase Fruit and Vegetable Intake: Consuming a variety of fruits and vegetables enriches the diet with vital antioxidants, such as vitamins C and E, which combat oxidative stress and may lower inflammation in the prostate. The fiber content also supports digestive health, potentially reducing the risk of weight gain and associated BPH risks.
  • Limit Red Meat and High-Fat Dairy Products: Diets high in red meat and saturated fats from dairy have been linked to an increased risk of prostate issues. Reducing these foods in favor of leaner protein sources and low-fat dairy options can help decrease the risk of prostate enlargement and improve heart health.
  • Eat More Fish: The omega-3 fatty acids in fatty fish are crucial for reducing inflammation, a key factor in prostate health. Regular consumption of omega-3-rich fish supports anti-inflammatory processes, which can be beneficial in managing the symptoms and progression of BPH. [PMC5736071]
  • Include Soy and Legumes: Soy products and legumes contain phytoestrogens, plant-based compounds that mimic estrogen in the body. These can help balance hormone levels, potentially mitigating the hormonal triggers associated with prostate growth and BPH symptoms. [PMC5793268]
  • Reduce Caffeine and Alcohol: Both substances can stimulate urine production and irritate the urinary tract, exacerbating symptoms like urgency and frequency. Moderating their intake, especially in the evening, can help manage these symptoms and improve sleep quality.
  • Stay Hydrated, But Don’t Overdo It: While proper hydration is vital for overall health, drinking too much fluid, especially before bedtime, can increase nocturia. Balancing fluid intake throughout the day and reducing it in the hours before sleep can help minimize disruptive nighttime bathroom visits.

Lifestyle Factors:

  • Regular Exercise: Engaging in consistent physical activity enhances blood flow, reduces stress, and can help manage hormone levels, all of which contribute to reducing the risk and severity of BPH symptoms. Activities like walking, swimming, or cycling are excellent choices for maintaining prostate health.
  • Maintain a Healthy Weight: Excess body fat, particularly around the waist, can increase hormone levels that may promote prostate enlargement. Weight loss achieved through a balanced diet and regular exercise can help improve urinary symptoms and overall health.
  • Pelvic Floor Exercises: Also known as Kegel exercises, these involve tightening and releasing the muscles that control urine flow. Strengthening these muscles can help improve urinary control, reduce urinary incontinence, and potentially alleviate some of the discomfort associated with BPH.
  • Manage Stress: Chronic stress can affect the body in numerous ways, including exacerbating BPH symptoms. Techniques like meditation, deep breathing exercises, and yoga not only reduce stress levels but also improve overall well-being, which can help manage BPH symptoms more effectively.
  • Timed Voiding and Bladder Training: This strategy involves urinating at set times to train the bladder, which can help reduce the frequency and urgency of urination. Keeping a diary to track urination patterns can be helpful in establishing a routine that minimizes the inconvenience and discomfort of BPH-related urinary symptoms.

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. This article aims to offer valuable insights into which nutritional supplements have undergone scientific study and shown promise in supporting specific health conditions. We break down the research, so you can work with your medical providers to make informed decisions about adding supplements to your health regimen. For personalized advice tailored to your needs, we recommend consulting with a registered dietitian in addition to your primary care provider.

Check with your physician when adding supplements. While supplements are generally safe for most people, do not add nutritional supplements without your physician’s specific approval if you are pregnant or nursing, are undergoing cancer treatment, have a history of organ transplant, liver or kidney disease, or take medications that interact with supplements.


  • Saw Palmetto: Saw palmetto (Serenoa repens) is a widely used herbal supplement known for its potential in promoting prostate health. At research doses between 320 and 960 mg per day for a minimum 3 to 5.5 months [PMC5049653], several studies suggest that it may help alleviate the bothersome symptoms associated with BPH, such as frequent urination and reduced urinary flow. [PMC6859144]. It also is found to increase average flow rate values and decrease prostate volume and mean prostate symptom score. [PMID: 28991765]
  • Beta-Sitosterol: Beta-sitosterol, a natural plant sterol present in certain foods and available as a supplement, has garnered attention for its possible role in improving urinary symptoms related to BPH. Researchers have explored its effectiveness in enhancing urinary flow and overall prostate health. [PMC4567552] At a minimum dosage of 130 mg per day for minimum 6 months [PMID: 9313662] Beta-sitosterol has been shown to improve prostate symptom score  [PMID: 10792163]
  • Pygeum: Derived from the bark of the African plum tree, pygeum is a herbal remedy often employed for managing BPH. Its traditional use stems from its potential to reduce urinary symptoms associated with prostate enlargement, particularly nighttime urination. [PMC7032619] Pygeum (Pygeum africanum) At a dose of 100 mg per day for a minimum of 2 months, prostate symptom scores and quality of life scores were improved in men with symptoms related to BPH patients at a dose of 100 mg daily. [PMID: 10475357]
  • Zinc: Zinc is an essential mineral vital for maintaining prostate health. While adequate zinc intake is necessary, it’s important to exercise caution and avoid excessive supplementation, as too much zinc can have adverse effects. [PMC7424038]
  • Vitamin D: Emerging research has hinted at the significance of vitamin D in prostate health. Ensuring sufficient vitamin D levels, whether through exposure to sunlight or supplements under healthcare guidance, may be beneficial for overall prostate well-being. [PMID: = 33213976] Vitamin D dosages should be adjusted based on your blood level with many clinicians recommending an optimal Vitamin D level of 50-80 ng/ml. Vitamin D Labs can be ordered in the NutriScape Lab Shop.
  • Lycopene: Lycopene, an antioxidant found in tomatoes and tomato products, has attracted interest for its potential protective role in prostate health. It is believed to help combat oxidative stress and inflammation in the prostate gland. [PMID: 32233234] Lycopene at research dosages around 15 or 20 mg per day for a minimum of 6 months might decrease the progression of BPH [PMID: 18156403] and correlates with lower cancer risk. [PMC4616444]
  • Pumpkin Seed Extract: Extracted from pumpkin seeds, this supplement has been studied for its potential to alleviate urinary symptoms associated with BPH. Research suggests that it may contribute to improved urinary function and overall prostate comfort. [PMID: 25196580]
  • Stinging Nettles: At a dose of 459 mg nettle root extract, stinging nettle is effective in decreasing prostate symptom scores and median residual urine volume. [PMID: 15045190]

Supplement Safety Information

Natural supplements like saw palmetto, beta-sitosterol, pygeum, zinc, vitamin D, lycopene, pumpkin seed extract, and stinging nettles are often seen as safe options, especially for helping with an enlarged prostate (BPH). These supplements come from plants and minerals and have a long history of use for supporting a healthy prostate and easing urinary problems that come with BPH. Research and people’s experiences show that when these supplements are taken in the right amounts, there are usually few side effects, and most people find them easy to take.

Medication Interactions:

  • Blood Thinners (Warfarin, Aspirin): Saw palmetto, stinging nettles, and vitamin E (often associated with lycopene supplementation) may increase the risk of bleeding when taken with blood thinners due to their potential to also thin the blood.
  • Hormone Therapies (Estrogens, Testosterone Blockers): Saw palmetto and beta-sitosterol may interact with hormone therapies by affecting hormone levels, potentially diminishing the effectiveness of these medications.
  • Antihypertensives (ACE Inhibitors, Beta-Blockers): Stinging nettles may lower blood pressure, potentially leading to additive effects with antihypertensive drugs and resulting in blood pressure that is too low.
  • Diabetes Medications (Metformin, Insulin): Zinc can lower blood sugar levels, which might enhance the effects of diabetes medications and increase the risk of hypoglycemia.
  • Antibiotics: Zinc can interfere with the absorption of certain antibiotics like tetracycline and quinolone antibiotics, potentially reducing their effectiveness.

Supplement Interactions:

  • Saw Palmetto: May enhance the effects of beta-sitosterol and pygeum, as all can impact hormone levels and prostate health, potentially leading to an additive effect.
  • Beta-Sitosterol: Similar to saw palmetto, combining with pygeum might increase their collective impact on prostate health, necessitating dosage adjustments.
  • Pygeum: When taken with saw palmetto and beta-sitosterol, might amplify the effects on prostate health due to similar mechanisms of action.
  • Zinc: High doses can interfere with copper absorption, so taking copper supplements might be necessary to prevent deficiency. Combining with calcium or iron supplements can reduce the absorption of both zinc and the other mineral.
  • Vitamin D: Taking with magnesium supplements can enhance vitamin D’s effectiveness, as magnesium is essential for vitamin D metabolism. High doses of vitamin A can interfere with vitamin D’s function in the body.
  • Lycopene: Absorption can be enhanced when taken with fatty acids, so combining it with omega-3 supplements might improve its bioavailability.
  • Pumpkin Seed Extract: Its effects on urinary health may be enhanced when taken with saw palmetto or stinging nettles.
  • Stinging Nettles: May enhance the diuretic effect of dandelion root supplements, potentially leading to increased urination and dehydration risk if not monitored.

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Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Managing prostate enlargement, or benign prostatic hyperplasia (BPH), can be effectively supported with the right dietary supplements alongside conventional treatments. Saw palmetto, beta-sitosterol, pygeum, zinc, vitamin D, lycopene, pumpkin seed extract, and stinging nettles have all shown promise in supporting prostate health, alleviating symptoms of BPH, and improving quality of life.

While these supplements offer a natural approach to managing prostate enlargement, always remember that they should complement, not replace, the advice and treatment plan provided by a healthcare professional. Embracing a holistic approach that combines the power of nutrition, lifestyle changes, and medical guidance can pave the way toward optimal prostate health and overall well-being.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


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