Nettle: Turning A Stinging Nuisance Into Potential Allergy Relief and More

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Nettle, sometimes overshadowed by more common (and less irritating) herbs, offers numerous health benefits worth investigating. With its nutrient-rich composition and potential therapeutic qualities, this plant provides a natural option for addressing various health issues. In this article, we’ll examine the scientifically supported advantages of adding nettle supplements to your daily regimen, highlighting how this plant can contribute to overall health.

What Is Nettle?

Nettle, scientifically known as Urtica dioica, is a perennial flowering plant native to Europe, Asia, Africa, and North America. Despite its reputation for causing painful stings upon contact with its leaves, nettle has been valued for centuries for its medicinal properties. Traditionally used in folk medicine, every part of the nettle plant – from its roots to its seeds – has been utilized for various health purposes.

Nettle leaves are characterized by their serrated edges and fine hairs that release histamine and other chemicals upon contact with the skin, irritating. However, when processed and consumed as a supplement, these same leaves offer a host of health benefits without the discomfort. Rich in vitamins, minerals, and bioactive compounds, nettle supplements have gained recognition for their potential to support overall health.

What Are the Benefits of Nettle?

  • Allergy Relief: Nettle supplements may help alleviate symptoms of seasonal allergies, such as sneezing, runny nose, and itching, due to their ability to inhibit histamine release. PMID: 19140159
  • Joint Support: Some studies suggest that nettle supplements may aid in relieving symptoms of arthritis, including joint pain and stiffness, possibly due to its anti-inflammatory properties. [PMC1298033]
  • Prostate Health: Nettle root extract has been investigated for its potential benefits in supporting prostate health and relieving symptoms of benign prostatic hyperplasia (BPH). PMC3589769 At a dose of 459 mg nettle root extract, stinging nettle is effective in decreasing prostate symptom scores and median residual urine volume. [PMID: 15045190]
  • Diuretic Effects: Nettle has diuretic properties, which may help promote urine flow and alleviate symptoms of urinary tract conditions, such as urinary tract infections and kidney stones.
  • Blood Sugar Regulation: Preliminary research shows that nettle supplements may help regulate blood sugar levels, might benefit persons with diabetes or those at risk of developing the condition. A study on Urtica dioica extract in diabetic women showed that after eight weeks, it improved key health markers by reducing blood glucose and triglycerides, and increasing good cholesterol and antioxidant levels. PMID: 28078249
  • Metabolic Syndrome: This is a health condition that includes high blood pressure, unhealthy cholesterol levels, and high blood sugar that increase the risk of heart disease, diabetes, and stroke. Nettle improves metabolic syndrome by affecting blood vessel and heart functions, cholesterol production, and blood sugar regulation. [PMC9282742]
  • Skin Health: Topical applications of nettle extract have been explored for their potential in treating various skin conditions, including eczema, acne, and wounds, thanks to its anti-inflammatory and antioxidant properties. PMC10672499
  • Hair Health: Nettle supplements are believed to promote hair growth and combat hair loss by inhibiting the production of the hormone DHT (dihydrotestosterone), which is associated with hair loss.
  • Digestive Support: Nettle has been traditionally used to aid digestion and relieve gastrointestinal discomfort, such as bloating, gas, and indigestion.
  • Immune Support: The immune-boosting properties of nettle supplements may help strengthen the body’s defense mechanisms and promote overall immune health. Urtica dioica agglutinin (UDA), a protein from stinging nettle, effectively blocks several strains of the COVID-19 virus by attaching to and disabling its entry mechanism. This makes UDA a promising candidate for treating and preventing COVID-19 infections across its various mutations. PMC9468479
  • Menstrual Support: Some women use nettle supplements to alleviate symptoms of premenstrual syndrome (PMS) and menstrual cramps, thanks to their anti-inflammatory and analgesic effects.
  • Anti-inflammatory Properties: Compounds found in nettle, such as flavonoids and carotenoids, exhibit anti-inflammatory effects, possibly reducing inflammation in the body. PMC9253158
  • Antioxidant Activity: Nettle contains antioxidants like polyphenols and flavonoids, which help neutralize harmful free radicals in the body, and could reduce the risk of chronic diseases. PMC9253158

Are Nettle Supplements Safe?

Stinging nettle supplements are widely recognized as safe when used as directed. Their safety profile is well-established, with a long history of use in traditional herbal medicine emphasizing minimal adverse effects. In clinical settings, stinging nettle has shown a high tolerance among users. Side effects are uncommon and when they do occur, they are generally mild, such as minor digestive discomfort or skin irritation. It’s always advisable to consult with healthcare providers before beginning any new supplement regimen, but stinging nettle stands out for its reliable safety in appropriate doses.

Medication Interactions with Nettle

  • Blood Thinners (Anticoagulants): Nettle may increase the risk of bleeding when taken concomitantly with blood-thinning medications like warfarin, heparin, or aspirin, which might lead to excessive bleeding or bruising.
  • Blood Pressure Medications: Nettle supplements may lower blood pressure levels, so combining them with antihypertensive medications could result in hypotension (low blood pressure).
  • Diabetes Medications: Nettle supplements may lower blood sugar levels, so concurrent use with diabetes medications could enhance their effects, possibly leading to hypoglycemia (low blood sugar).
  • Diuretics: Nettle has diuretic properties, and combining it with other diuretic medications may increase the risk of dehydration and electrolyte imbalances.
  • Lithium: Nettle may decrease the excretion of lithium, leading to increased lithium levels in the body and potential toxicity.

Supplement Interactions with Nettle

  • Iron Supplements: Nettle supplements may enhance iron absorption, so combining them with iron supplements could increase iron levels in the body, leading to iron overload in some persons.
  • Herbal Diuretics: Since nettle itself acts as a diuretic, combining it with other herbal diuretics may increase the risk of dehydration and electrolyte imbalances.
  • Antidiabetic Supplements: Nettle supplements may lower blood sugar levels, so combining them with other antidiabetic supplements could enhance their effects, possibly leading to hypoglycemia (low blood sugar).
  • Herbal Blood Thinners: Nettle may have anticoagulant properties, so combining it with other herbal blood thinners could increase the risk of bleeding.

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Stinging Nettle Root Extract 250mg by NOW Foods

Stinging Nettle has been used according to tradition, since the days of Caesar 2,000 years ago. NOW® Stinging Nettle Root is produced to meet the highest European standards, where it has been researched and widely used. Supports Prostate Health* Suggested Use: Take 2 capsules 1 to 2 times daily.

Amount per 2 Capsule Serving

Stinging Nettle Extract … 500mg (Urtica dioica) (Root)


Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

What To Eat

To Sum It Up

Incorporating nettle supplements into your wellness routine can offer a plethora of health benefits. From its anti-inflammatory properties to its potential to support hair health and promote immune function, nettle stands as a natural powerhouse in the realm of herbal remedies. Whether you’re seeking relief from allergies, joint discomfort, or looking to bolster your overall health, nettle supplements provide a natural and holistic approach to health maintenance. With its rich nutrient profile and time-tested traditional use, nettle emerges as a versatile and valuable addition to a healthy lifestyle.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


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