Non-Celiac Gluten Intolerance: Key Strategies for Food and More

Secure Ordering | Free Shipping | 20% Off Retail Prices

Along with providing information on whether gluten intolerance supplements might be right for you, this article also links to Fullscript where you can buy supplements for gluten intolerance online through the secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

Living with gluten intolerance means sticking to a gluten-free diet, but sometimes, diet alone doesn’t cover all the bases. Nutritional deficiencies can arise from restricted food choices and persistent symptoms can still be a part of everyday life. In this article, we’re going to explore a variety of supplements that can support your digestive health, boost nutrient absorption, and reduce inflammation. These tools can improve the quality of life for anyone dealing with gluten intolerance, giving you more than just dietary changes to rely on. Whether you’ve just been diagnosed or you’re looking to enhance your current health regimen, discovering how specific supplements can help manage the challenges of gluten intolerance could be a crucial turning point.

What Is Non-Celiac Gluten Intolerance?

Non-Celiac Gluten Intolerance, also known as gluten sensitivity, occurs when individuals experience negative reactions to gluten-containing foods without having celiac disease or wheat allergy. Common symptoms include discomfort in the stomach like bloating, abdominal pain, diarrhea, or constipation, as well as fatigue, headaches, joint pain, and skin issues like eczema.

The precise cause of non-celiac gluten intolerance remains uncertain, but it’s believed to involve a combination of genetic, environmental, and immune system factors. Research suggests that certain components of gluten, such as FODMAPs, may trigger symptoms in sensitive individuals. Additionally, changes in gut bacteria or increased intestinal permeability could contribute to its development.

Non-celiac gluten intolerance affects a significant number of people and can significantly impact their quality of life. If you suspect you may have gluten intolerance, it’s crucial to consult with a healthcare professional for proper evaluation and management.

What Causes Non-Celiac Gluten Intolerance?

Non-celiac gluten sensitivity (NCGS), also known as non-celiac wheat sensitivity (NCWS), is a condition that causes individuals to experience symptoms similar to those of celiac disease when they consume gluten, but without the autoimmune response or intestinal damage observed in celiac disease. The exact cause of non-celiac gluten intolerance remains unclear, but several theories attempt to explain the mechanisms behind this condition:

• Immune Response: While it is not an autoimmune condition like celiac disease, some researchers believe that NCGS may involve an innate immune response. This response is less specific and more immediate than the adaptive immune response seen in celiac disease, and it does not involve the production of antibodies against tissue transglutaminase.
• FODMAPs: Some symptoms attributed to NCGS may actually be a response to fermentable oligo-, di-, mono-saccharides, and polyols (FODMAPs), which are found in a range of foods including wheat. Wheat is a major source of fructans, a type of FODMAP. Individuals who are sensitive to FODMAPs may experience symptoms of irritable bowel syndrome (IBS), which are similar to those reported for NCGS.
• Gut Microbiota: Alterations in the gut microbiota and its interactions with the immune system and the intestinal mucosa may play a role in the development of NCGS. Some individuals may have a gut microbiota composition that reacts negatively to gluten or other wheat components.
• Other Wheat Components: Besides gluten, wheat contains other proteins, such as amylase-trypsin inhibitors (ATIs), which can cause inflammation and worsen symptoms in sensitive individuals. This suggests that some people may react not only to gluten but to other components of wheat and related grains.

Research into NCGS is ongoing, and understanding of the condition continues to evolve. Diagnosing NCGS typically involves ruling out celiac disease and wheat allergy and observing whether symptoms improve on a gluten-free diet and return when gluten is reintroduced. [PMC8224613, PMC6630947]

What Food and Lifestyle Factors Are Important For Managing Gluten Intolerance?

• Gluten-Free Diet: Avoid wheat, barley, rye, and their derivatives; opt for gluten-free alternatives like fruits, vegetables, lean proteins, dairy products, and gluten-free grains.
• Read Labels: Check food labels for hidden sources of gluten and look for gluten-free certification symbols on packaging.
• Cooking at Home: Prepare meals using fresh, whole ingredients to minimize the risk of gluten contamination.
• Cross-Contamination Awareness: Use separate utensils, cutting boards, and cooking surfaces for gluten-free foods; clean kitchen surfaces thoroughly before preparing gluten-free meals.
• Gluten-Free Alternatives: Explore gluten-free options for bread, pasta, flour, and baking mixes available in supermarkets and specialty stores.
• Nutrient-Rich Diet: Consume a balanced diet rich in fruits, vegetables, lean proteins, healthy fats, and gluten-free whole grains.
• Stay Hydrated: Drink plenty of water throughout the day and avoid sugary beverages and alcohol.
• Manage Stress: Incorporate stress-reducing activities like yoga, meditation, or hobbies into your daily routine.
• Seek Support: Connect with support groups, online communities, or healthcare professionals specializing in gluten intolerance for guidance and emotional support.
• Avoid Alcohol: Alcohol increases leaky gut. [PMC9028931]

What Nutritional Supplements Are Recommended For Non-Celiac Gluten Intolerance?

• Probiotics: Probiotic supplements may help improve gut health and alleviate gastrointestinal symptoms associated with gluten intolerance, such as bloating, gas, and diarrhea. [PMC9028931]
• Polyphenols: Studies suggest that polyphenols, which are natural compounds found in fruits, vegetables, and whole grains, might help ease the symptoms of non-celiac gluten sensitivity. These benefits are thought to come from polyphenols’ ability to calm inflammation and strengthen the gut barrier. [PMC9268201]
• Omega-3 Fatty Acids: Omega-3 fatty acids have anti-inflammatory properties and may help reduce inflammation in the body, which can be beneficial for individuals with gluten intolerance experiencing inflammatory symptoms. [PMC7835870]
• Glutamine: Glutamine is an amino acid that plays a crucial role in maintaining the integrity of the intestinal lining. Some people with gluten intolerance may use glutamine supplements to support gut health and promote healing of the digestive tract. [PMC6835310,PMC4369670]
• Digestive Enzymes: Digestive enzyme supplements containing enzymes such as amylase, protease, and lipase may help improve digestion and alleviate gastrointestinal symptoms like bloating and discomfort. [PMC9862683]
• Curcumin: Turmeric contains a compound called curcumin, which has anti-inflammatory properties. Some individuals with gluten intolerance may use turmeric or curcumin supplements to help reduce inflammation and alleviate symptoms such as joint pain or inflammation in the gut. [PMC5407015]
• Multivitamin and Mineral Supplement: A high-quality multivitamin and mineral supplement can help fill in any nutritional gaps in the diet caused by restrictions on gluten-containing foods.
  • Vitamin D: Many people with gluten intolerance may have low levels of vitamin D due to limited sun exposure or impaired absorption. Supplementing with vitamin D can support bone health and immune function. [PMC9028931]
  • B Vitamins: B vitamins, including B6, B12, and folate, are important for energy production, nervous system function, and red blood cell formation. Since gluten-containing grains are a significant source of B vitamins, individuals on a gluten-free diet may benefit from supplementation.
  • Zinc: Zinc is an essential mineral involved in immune function, wound healing, and gastrointestinal health. Some people with gluten intolerance may use zinc supplements to address deficiencies or support immune function. [PMC9028931]
• Iron: Iron deficiency is more common in individuals with gluten intolerance, especially those with gastrointestinal symptoms like chronic diarrhea or malabsorption. Iron supplements can help replenish iron stores and prevent anemia.

Order Supplements For Non-Celiac Gluten Intolerance

Why Professionals Choose the Fullscript Formulary

Your health is on the line. Health professionals know that many other online and retail options set a very low bar for quality–sometimes amazingly low. The Fullscript formulary is the most secure online source for the highest quality brands securely sourced to assure freshness and purity. Here’s what makes Fullscript the best:

• Meticulous vetting of brand quality. Health professionals trust Fullscript to continuously monitor the quality of each item on the platform. Other retailers operate with profit as their highest or only motive when choosing brands. Fullscript cares only about quality and reliability. Unlike discount stores, large online marketplaces, and other retailers you won’t find ingredients sourced from China or other questionable locations or companies.
• Always 20% Discount off the manufacturer’s retail price. When you follow any link from Supplement-Sciences.com, you will automatically get 20% off the retail price.
• Free shipping over $50.
• Freshness. Fullscript prioritizes freshness over bulk buying even if it means an increased risk of briefly being out of stock.
• Top quality phone and online support. When you call, knowledgeable humans at Fullscript answer your questions.
• How It Works:
  • Easy Sign-up & No Spam Email: Click the “View Product” button below to be taken to Fullscript’s login page where you can quickly create your secure account with just your name, email, and phone number. Then you will be taken directly to the product page.
  • Wide variety of supplement options: Once you sign in to your account, you are not limited to the products listed below. You will see similar items listed at the bottom of each product page on Fullscript.
  • Search For What You Want: Once inside Fullscript, you can search for the exact brands and products you want from their wide selection of quality brands.

When you purchase linked products presented on this page, Supplement Sciences, LLC receives affiliate fees so that our dietitians can continue to create great content.

Thank you for your support!

Supplement Safety Information

For individuals with non-celiac gluten intolerance, supplements such as multivitamins and mineral supplements, vitamin D, B vitamins, iron, calcium, probiotics, omega-3 fatty acids, digestive enzymes, glutamine, turmeric/curcumin, L-glutathione, methylated B vitamins, and zinc can be safe and beneficial additions to their diet. These supplements can help address potential nutrient deficiencies, support immune function, promote gut health, and reduce inflammation without containing gluten or exacerbating symptoms of gluten intolerance. When used appropriately and under the guidance of a healthcare professional, these supplements can complement a gluten-free lifestyle and contribute to overall well-being for individuals with non-celiac gluten intolerance.

Medication Interactions:

• Antibiotics: Taking probiotic supplements may reduce the effectiveness of antibiotics by interfering with their action on harmful bacteria. It’s advisable to take probiotics several hours apart from antibiotic doses to avoid this interaction.
• Blood-thinning Medications (e.g., Warfarin, Aspirin): Omega-3 fatty acid supplements, such as fish oil, may increase the risk of bleeding when taken with blood-thinning medications like warfarin or aspirin. Close monitoring of blood clotting parameters is recommended in such cases.
• Antacids or Proton Pump Inhibitors: Taking iron supplements with antacids or proton pump inhibitors may reduce iron absorption and efficacy. It’s advisable to take iron supplements with vitamin C or on an empty stomach to enhance absorption and minimize interactions.
• Anticonvulsants: Certain B vitamins, particularly B6, may interact with anticonvulsant medications, possibly altering their effectiveness or increasing the risk of side effects. Close monitoring and adjustment of B vitamin supplementation may be necessary in these cases.
• Chemotherapy Drugs: Glutamine supplements may interact with chemotherapy drugs, affecting their effectiveness or metabolism. It’s essential to discuss potential interactions with a healthcare professional before starting glutamine supplementation.
• Methotrexate: Methylated B vitamins may interact with methotrexate, could alter its effectiveness or increasing the risk of side effects. Close monitoring and adjustment of B vitamin supplementation may be necessary in individuals taking methotrexate.
• Diuretics: Zinc supplements may interact with diuretics, affecting their absorption or metabolism. It’s essential to discuss potential interactions with a healthcare professional before starting zinc supplementation.
• Nitroglycerin: L-glutathione supplements may interact with nitroglycerin, affecting its effectiveness or metabolism. It’s advisable to discuss potential interactions with a healthcare professional before starting L-glutathione supplementation.

Supplement Interactions:

• Multivitamin and Mineral Supplement:
  • Calcium: Taking calcium supplements with a multivitamin may interfere with the absorption of other minerals like iron or zinc.
  • Iron: Iron supplements in a multivitamin may reduce the absorption of calcium when taken together.
  • Zinc: Zinc supplements may compete with other minerals in a multivitamin for absorption, may reduce their effectiveness.
• Vitamin D:
  • Calcium: Vitamin D enhances calcium absorption, so taking them together can improve bone health.
  • Omega-3 Fatty Acids: Vitamin D may enhance the absorption and effectiveness of omega-3 fatty acids in supporting cardiovascular health.
• B Vitamins:
  • Iron: Vitamin B12 may improve the absorption of iron when taken together, which can be beneficial for individuals with iron deficiency.
  • Methylated B Vitamins: Methylated forms of B vitamins may enhance the absorption and utilization of other B vitamins in the body.
• Iron:
  • Vitamin C: Consuming vitamin C-rich foods or supplements alongside iron can enhance iron absorption and improve its effectiveness in addressing iron deficiency.
  • Calcium: Calcium supplements may interfere with the absorption of iron when taken together, so it’s advisable to take them at different times of the day.
• Calcium:
  • Vitamin D: Vitamin D helps regulate calcium absorption in the body, so taking them together can support bone health.
  • Magnesium: Calcium supplements may compete with magnesium for absorption, so it’s recommended to take them at different times to avoid interference.
• Probiotics:
  • Digestive Enzymes: Probiotics and digestive enzymes may work synergistically to support digestive health and alleviate gastrointestinal symptoms like bloating or indigestion.
• Omega-3 Fatty Acids:
  • Vitamin D: Vitamin D may enhance the absorption and effectiveness of omega-3 fatty acids in supporting cardiovascular health.
• Digestive Enzymes:
  • Probiotics: Probiotics and digestive enzymes may work synergistically to support digestive health and alleviate gastrointestinal symptoms like bloating or indigestion.
• Glutamine:
  • Turmeric/Curcumin: Glutamine and turmeric/curcumin supplements may complement each other in supporting gut health and reducing inflammation.
• Turmeric/Curcumin:
  • Glutamine: Glutamine and turmeric/curcumin supplements may complement each other in supporting gut health and reducing inflammation.
• L-Glutathione:
  • Methylated B Vitamins: Methylated B vitamins may support glutathione production in the body, enhancing its antioxidant and detoxification functions.
• Methylated B Vitamins:
  • L-Glutathione: Methylated B vitamins may support glutathione production in the body, enhancing its antioxidant and detoxification functions.
  • B Vitamins: Methylated forms of B vitamins may enhance the absorption and utilization of other B vitamins in the body.
• Zinc:
  • Multivitamin and Mineral Supplement: Zinc supplements may compete with other minerals in a multivitamin for absorption, possibly reducing their effectiveness.
  • Iron: Zinc supplements may interfere with the absorption of iron when taken together, so it’s advisable to take them at different times of the day.

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Incorporating Multivitamin and Mineral Supplements, Vitamin D, B Vitamins, Iron, Calcium, Probiotics, Omega-3 Fatty Acids, Digestive Enzymes, Glutamine, Turmeric/Curcumin, L-Glutathione, Methylated B Vitamins, and Zinc can offer significant health benefits for Non-Celiac Gluten Intolerance. However, it’s crucial to remember that supplements should complement a healthy diet and lifestyle, not replace them. Consultation with a Registered Dietitian can provide personalized guidance on supplement use, ensuring optimal health outcomes.

This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.