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Along with providing information on whether Vinpocetine supplements might be right for you, this article also links to Fullscript where you can buy supplements online through Fullscript’s secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

What Is Vinpocetine?

Vinpocetine is a synthetic compound derived from vincamine, a substance found in the periwinkle plant. It has gained attention for its potential effects on brain health and cognition. Unlike many natural supplements, vinpocetine is not found naturally in foods; it is produced explicitly for use in dietary supplements.

What Are the Benefits of Vinpocetine?

Vinpocetine, might have benefits in cognitive health and circulation, [PMC5766389] but much of the research cited here is done in animal models. Here’s a look at the possible health benefits associated with Vinpocetine:

  • Enhances Cognitive Function: In animal models, Vinpocetine is most known for its potential to improve memory, concentration, and overall cognitive function, making it popular among those seeking cognitive enhancement.
    • May Help with Age-Related Cognitive Decline: Due to its potential cognitive benefits and neuroprotective properties, Vinpocetine is sometimes considered for managing age-related cognitive decline.
    • Improves Blood Flow to the Brain: It is believed to increase cerebral blood flow, which can help in better oxygen and nutrient delivery to the brain, supporting its function.
    • Potential in Managing Alzheimer’s Disease: Early research suggests that Vinpocetine might have a role in the management of Alzheimer’s disease due to its neuroprotective and cerebral blood flow enhancing properties. A Cochrane review stated study results show benefit associated with treatment with vinpocetine 30 mg/day and 60 mg/day compared with placebo. [PMC8406981]
    • Neuroprotective Properties: Vinpocetine may protect brain cells against damage caused by excessive calcium influx, oxidative stress, and toxic environmental factors. [PMC10018848]
    • Potential in Stroke Recovery: Some studies suggest that Vinpocetine might aid in the recovery process after a stroke by improving blood flow and reducing inflammation in the brain.
    • Anti-Inflammatory Effects: It possesses anti-inflammatory properties, which can be beneficial in reducing inflammation in the brain and other parts of the body.
  • Supports Vision Health: There is some evidence that Vinpocetine may improve vision and eye health by enhancing blood flow to the eyes.
  • Tinnitus and Inner Ear Conditions: There is some evidence that Vinpocetine may improve symptoms of tinnitus and certain inner ear disorders by improving blood circulation in these areas.
  • Menstrual Pain Relief: Anecdotal reports and preliminary research indicate that Vinpocetine might help alleviate menstrual pain, potentially due to its anti-inflammatory effects.
  • Epilepsy and Seizure Disorders: Some studies have explored Vinpocetine’s potential in reducing the frequency and severity of seizures in epilepsy, but more research is needed in this area.
  • Reduction of Symptoms of Parkinson’s Disease: Given its neuroprotective properties, Vinpocetine is also being explored for its potential benefits in Parkinson’s disease.

Is Vinpocetine Safe?

Vinpocetine is generally regarded as safe for consumption when used appropriately. It has been extensively studied and used in various parts of the world, with a good safety record in controlled dosages. Most people who take vinpocetine experience no adverse effects, and when side effects do occur, they are typically mild and transient, such as minor gastrointestinal disturbances or headaches. However, safety in pregnant or nursing women, children, and those with severe renal or hepatic impairment has not been established, underscoring the importance of professional advice in these cases.

Medication Interactions with Vinpocetine

  • Blood Thinners (Anticoagulants and Antiplatelets): Vinpocetine may enhance the blood-thinning effects, increasing the risk of bleeding.
  • Aspirin: Similar to blood thinners, combining vinpocetine with aspirin can increase bleeding risk.
  • Warfarin: The use of vinpocetine with warfarin might increase the chances of bleeding and affect blood clotting parameters.
  • Clopidogrel: Taking vinpocetine with clopidogrel can potentially elevate the risk of bleeding.
  • Ibuprofen and Other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs combined with vinpocetine might increase gastrointestinal bleeding risk.
  • Blood Pressure Medications: Vinpocetine can enhance the effects of these medications, leading to hypotension (low blood pressure).
  • Immune Suppressants: There may be potential interactions with these drugs, but specific effects are less clear and require further research.

Supplement Interactions with Vinpocetine

  • Ginkgo Biloba: Vinpocetine and Ginkgo Biloba together may increase the risk of bleeding due to their combined blood-thinning effects.
  • Garlic Supplements: Similar to Ginkgo Biloba, garlic supplements may also enhance the risk of bleeding when taken with vinpocetine.
  • Omega-3 Fatty Acids (Fish Oil): These supplements, known for their blood-thinning properties, might further elevate the risk of bleeding in combination with vinpocetine.
  • Coenzyme Q10 (CoQ10): There is a potential for increased bleeding risk when CoQ10 is taken alongside vinpocetine.
  • St. John’s Wort: This supplement might interfere with the metabolism and effectiveness of vinpocetine.
  • Ginseng: Ginseng may amplify the blood-thinning effect of vinpocetine, increasing the risk of bleeding.
  • Vitamin E: High doses of Vitamin E, combined with vinpocetine, could potentially increase bleeding tendencies.

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Vinpocetine 20mg by Pure Encapsulations

Vinpocetine supports healthy cognitive function while promoting healthy blood flow and oxygen utilization. Vinpocetine specifically helps distribute oxygen to cells.*

  • Supports cognitive function and cerebrovascular health*
  • Promotes memory function*
  • Made with hypoallergenic, vegetarian ingredients

Vinpocetine is an alkaloid synthesized from vincamine, a natural compound extracted from the leaves of periwinkle (Vinca minor L) which was first developed in Europe over 20 years ago. Vinpocetine is absorbed in the small intestine and then processed in the liver. Once in systemic circulation, vinpocetine is absorbed by most tissues in the body and crosses the blood brain barrier. Vinpocetine enhances healthy cerebrovascular blood flow, possibly by supporting cyclic GMP phosphodiesterase activity, allowing for healthy oxygen distribution to cells. Vinpocetine may also support oxygen release from hemoglobin, providing cells easier access to the oxygen they need. Furthermore, studies have reported that vinpocetine may provide neuroprotection via its antioxidant properties. In a double blind placebo-controlled clinical trial, 84 elderly subjects were given vinpocetine or a placebo over a period of 90 days. Results indicated that those supplementing with vinpocetine experienced positive cognitive function. An additional placebo-controlled, randomized, double blind, multicenter trial of 203 individuals suggested that vinpocetine significantly enhanced cognition and other subjective measures. Vinpocetine has the potential to support healthy memory, as indicated by a randomized, double blind, crossover study.*

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Vinpocetine supplements, derived from the periwinkle plant, offer a range of health benefits. They are primarily known for enhancing cognitive functions, potentially improving memory, focus, and mental clarity through improved blood flow to the brain. Beyond cognitive support, vinpocetine’s neuroprotective properties, stemming from its anti-inflammatory and antioxidant effects, are valuable in safeguarding brain cells. This makes it a noteworthy option for those interested in brain health and cognitive maintenance.

This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.

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