Velvet Bean (Mucuna Pruriens)

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Along with providing information on whether Velvet Bean (Mucuna Pruriens) supplements might be right for you, this article also links to Fullscript where you can buy supplements online through Fullscript’s secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

Velvet bean, known scientifically as Mucuna pruriens, is a tropical bean with hairy pods and striking purple to black seeds. Velvet bean is a powerhouse of nutrients and compounds that have been linked to an impressive array of health advantages. Traditionally used in Ayurvedic medicine, velvet bean’s potential to enhance mood, increase libido, and improve overall vitality is sparking interest from people looking for natural health solutions. Let’s dive into the many of ways velvet bean might contribute to your health and why it might deserve a spot in your supplement regimen.

What Is Velvet Bean?

Velvet bean can be both a supplement and a food. As a food, it has been traditionally used in some cultures, where it’s cooked and prepared in specific ways to reduce its potential toxins. Velvet Bean, also known as Mucuna Pruriens or cowhage, is a tropical legume native to Africa and tropical regions in Asia. It’s well known for its lush, velvet-like coating of hairs that can cause severe itching if they come in contact with skin. However, the importance of this plant goes beyond its unique appearance.

Inside the bean pods of the Mucuna Pruriens plant, there are seeds that have been used for centuries in traditional medicine, particularly in Ayurvedic medicine from India. The seeds are rich in a compound called L-Dopa, which is a direct precursor to dopamine, a neurotransmitter in the brain that plays a significant role in mood, memory, and overall brain health.

What are the Benefits of Velvet Bean?

  • Parkinson’s Disease Management: Mucuna Pruriens is a natural source of L-Dopa, a compound that is converted to dopamine in the brain. Dopamine levels are typically low in people with Parkinson’s disease, and Mucuna Pruriens might help increase these levels. [PMC5539737][PMID: 35380400]
  • Mood Enhancement: Because of its effect on dopamine production, Mucuna Pruriens may help improve mood and reduce symptoms of depression. However, more research is needed to fully understand this effect.
  • Fertility and Libido: Traditional medicine often uses Mucuna Pruriens to boost fertility, particularly in men. It’s thought to increase testosterone levels and sperm count, although more studies are needed to confirm these benefits.
  • Antioxidant Effects: Mucuna Pruriens has antioxidant properties, meaning it can help neutralize potentially harmful free radicals in the body. This might contribute to overall better health and protection against certain diseases.
  • Stress Reduction: Some studies suggest that Mucuna Pruriens can reduce cortisol levels, the hormone often associated with stress. This could potentially help manage stress-related conditions.

Is Velvet Bean Safe?

Mucuna Pruriens, due to its high L-Dopa content, can interact with certain medications. Here’s a list of some potential interactions:

  • Levodopa/Carbidopa (Sinemet): Do not take this supplement if you take medication for Parkinson’s. Since Mucuna Pruriens naturally contains L-Dopa, the same active ingredient found in Parkinson’s disease medications like Sinemet, combining the two can lead to too much L-Dopa in the body. This could result in severe side effects like nausea, hallucinations, and erratic movements.
  • Antidepressants (particularly MAO inhibitors): Do not take this if you take antidepressants. Antidepressants, especially monoamine oxidase inhibitors (MAOIs), can interact with Mucuna Pruriens, potentially leading to a dangerous increase in serotonin levels, a condition known as serotonin syndrome. Symptoms can range from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures).
  • Antipsychotics: Do not take with antipsychotic medications. Antipsychotics often work by blocking dopamine activity in the brain. Since Mucuna Pruriens can increase dopamine levels, it could potentially reduce the effectiveness of these medications.
  • Blood Pressure Medications: There’s some evidence that Mucuna Pruriens can lower blood pressure. If you’re already taking medication to lower your blood pressure, combining it with Mucuna Pruriens could cause your blood pressure to drop too low.

Medication Interactions

Mucuna Pruriens, due to its high L-Dopa content, can potentially interact with certain nutritional supplements. Here are a few possible interactions:

  • 5-HTP or St. John’s Wort: These supplements can increase serotonin levels. Combined with Mucuna Pruriens, which increases dopamine levels, this could theoretically lead to a condition called serotonin syndrome, characterized by high levels of serotonin, a type of neurotransmitter in the brain.
  • Dopamine Precursors (like Tyrosine or Phenylalanine): Since these supplements also increase dopamine levels, using them in combination with Mucuna Pruriens could potentially lead to too much dopamine. This could increase the risk of side effects associated with high dopamine levels.
  • Vitamin B6: Vitamin B6 can increase the conversion of L-Dopa (the active compound in Mucuna Pruriens) to dopamine. While this might seem beneficial, it could also mean that more L-Dopa is converted to dopamine outside of the brain, where it’s needed most. This could limit the effectiveness of Mucuna Pruriens.
  • Antioxidants (like Vitamin C and E): While the interactions between Mucuna Pruriens and antioxidants aren’t fully understood, it’s worth noting that both can influence dopamine levels. If taken together, they might have a synergistic or counteractive effect on dopamine, so it’s worth discussing with a healthcare provider.

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Mucuna Pruriens by Protocol for Life Balance

  • 400 mg – Velvet Bean Extract
  • Nervous System Support*
  • 15% Natural L-Dopa
  • Vegetarian/Vegan

Mucuna pruriens, commonly known as Velvet Bean, is a legume widely used in traditional Ayurvedic herbalism. M. pruriens is known to naturally possess the direct dopamine precursor, L-Dopa.* Dopamine is a neurotransmitter that helps to maintain normal brain and nervous system function and promotes a positive mood.* Unlike dopamine, L-Dopa can penetrate the blood-brain barrier and can be used by the brain to produce dopamine.* This product is standardized to a minimum of 15% L-Dopa.

Take 2 capsules with a meal, or as directed by your healthcare practitioner. Best when taken early in the day.

Serving Size: 2 Veg Capsules

Amount Per Serving
Velvet Bean Extract … 800mg
(Mucuna pruriens) (Seed) (min. 15% L-DOPA, naturally occurring)
L-DOPA … 120mg

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Velvet bean, also known as Mucuna Pruriens, offers a wide array of potential health benefits. From its potential role in enhancing mood and aiding in stress management, to its traditional use in supporting Parkinson’s treatment, and even its potential to boost fertility, velvet bean supplements encompass a broad spectrum of wellness-enhancing properties. Awareness of drug interactions is critical for the safe use of this supplement. As with any dietary supplement, it’s essential to consult with a healthcare provider to determine if velvet bean supplements align with your health needs and goals. With ongoing research, we continue to broaden our understanding of this ancient plant’s benefits, underscoring the important relationship between nature and human health.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


About the Author

Stephanie Figon, MS, RDN, LD

Founder of NutriScape.NET. As a dietitian since 1992, Steph Figon has had experiences in consulting, 15 years in clinical, and has operated a private practice nutrition counseling office for since 2011. Connect on Linkedin

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