What Folk Medicine Has To Say About the Benefits of Stone Root

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Stone Root, scientifically known as Collinsonia Canadensis, has a rich history of traditional use, deeply rooted in herbal medicine practices for generations. This perennial herb, native to North America, was utilized by indigenous communities and later adopted by herbalists for its supposed therapeutic properties. Today, its often lauded for a wide array of health benefits, from improving digestive health to easing the discomfort of kidney stones. However, despite its long-standing use in folk medicine, it doesn’t seem to have any scientific research in animal models or in humans. This is not to say that it does not work, but we find no data to support any health claims.

What Is Stone Root?

Stone root, also known as Collinsonia canadensis, is a plant native to North America. The name “stone root” comes from the plant’s supposed ability to treat kidney stones, and it’s known for its large, tuberous root system that’s hard and stone-like.

This perennial plant belongs to the mint family and has been used in traditional herbal medicine for centuries. It’s known for its beautiful, lemon-scented flowers and can often be found growing in wooded areas.

In terms of its medicinal uses, stone root has been traditionally used for a variety of health concerns. Some of these include improving digestion, treating kidney and bladder stones, and addressing issues like varicose veins and hemorrhoids. It’s believed to have diuretic properties (meaning it can help your body get rid of excess water) and has been used as a tonic for improving overall health.

What are the Benefits of Stone Root?

There has been some research on the chemistry of Stone Root: [PMC6313439], but there are currently no human studies demonstrating its benefits. However, Stone Root has still been a part of traditional medicine for use in a number of health conditions, including:

  • Digestive Health: No research was available, but stone root is often used in traditional medicine for various digestive issues. It’s believed to soothe the digestive tract and help with conditions such as constipation.
  • Circulatory Health: The plant has been used to help treat varicose veins and hemorrhoids, conditions often associated with poor circulation.
  • Respiratory Health: Some practitioners of traditional medicine use stone root to alleviate symptoms of laryngitis and bronchitis.
  • Anti-inflammatory Properties: Stone root is believed to have anti-inflammatory properties and has been used to alleviate symptoms related to inflammation.
  • Kidney and Bladder Health: Although stone root has been used historically to support kidney and bladder health, no published research was found.

What are Medication Interactions with Stone Root?

  • Diuretics: Stone Root may have diuretic properties and can enhance the effects of diuretic medications. This interaction can potentially lead to increased urine production and electrolyte imbalances. It is important to monitor your fluid and electrolyte levels when using Stone Root alongside diuretic medications and consult with your healthcare provider for appropriate dosage adjustments.
  • Blood Pressure Medications: Stone Root may have hypotensive (blood pressure-lowering) effects. When taken with blood pressure medications, it can further reduce blood pressure and potentially lead to excessively low blood pressure. Close monitoring of blood pressure levels is necessary, and adjustments to medication dosage may be required under the guidance of a healthcare professional.
  • Anticoagulant/Antiplatelet Medications: Stone Root has been reported to possess anticoagulant and antiplatelet properties. Taking Stone Root alongside anticoagulant or antiplatelet medications, such as warfarin or aspirin, may increase the risk of bleeding. It is essential to inform your healthcare provider if you are using Stone Root while on these medications to closely monitor your blood clotting parameters.
  • Diabetes Medications: Stone Root may have an impact on blood sugar levels, and combining it with diabetes medications, such as insulin or oral hypoglycemic agents, may affect blood sugar control. Regular monitoring of blood sugar levels and close communication with your healthcare provider are necessary to adjust medication dosage if needed.
  • Immunosuppressant Medications: Stone Root has immune-modulating properties, and combining it with immunosuppressant medications, such as corticosteroids or immunosuppressive drugs, may interfere with the effects of these medications. It is advisable to consult with a healthcare professional before using Stone Root if you are on immunosuppressant therapy.

What are Supplement Interactions with Stone Root?

  • Blood-Thinning Supplements: Stone Root may possess natural blood-thinning properties, and combining it with other blood-thinning supplements, such as fish oil or garlic supplements, can increase the risk of bleeding. It is important to monitor your blood clotting parameters and consult with a healthcare professional before combining Stone Root with any blood-thinning supplements.
  • Immune-Boosting Supplements: Stone Root has immune-modulating effects, and combining it with other immune-boosting supplements, such as echinacea or elderberry, may potentially enhance immune activity. It is advisable to consult with a healthcare professional before combining Stone Root with immune-boosting supplements to ensure appropriate dosing and avoid any potential adverse effects.
  • Diuretic Supplements: Stone Root itself possesses diuretic properties, and combining it with other diuretic supplements, such as dandelion or horsetail, can further increase urine production and potentially lead to electrolyte imbalances. It is essential to monitor your fluid and electrolyte levels and consult with a healthcare professional for appropriate dosage adjustments when using Stone Root alongside diuretic supplements.
  • Antioxidant Supplements: Stone Root contains various antioxidants, and combining it with other antioxidant supplements, such as vitamin C or resveratrol, may potentially enhance the overall antioxidant activity in the body.

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Collinsonia Root

Amount Per 2 Capsule Serving:
Stoneroot … 200mg
(Collinsonia canadensis) 
Milk Thistle Seed … 200mg
(Silybum marianum)
Calendula Flower … 200mg
(Calendula officinalis)
Marshmallow Root … 200mg
(Althaea officinalis) 
Dandelion Root … 150mg
(Taraxacum officinale)
Witch Hazel Leaf … 80mg
(Hamamelis virginiana)
Parsley Leaf … 80mg
(Petroselinum crispum)


To Sum It Up

While scientific research has yet to confirm the traditional wisdom surrounding Stone Root, many individuals continue to integrate this plant into their wellness routines. These individuals place a higher value on time-honored practices and anecdotal evidence than on scientifically validated claims, finding comfort and perceiving benefits in the remedies that have been passed down through generations. It’s a reminder that our choices in healthcare and wellness often go beyond what is measured or proven in a lab.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


About the Author

Stephanie Figon, MS, RDN, LD

Creator of Supplement Sciences and NutriScape.NET. As a dietitian since 1992, Steph has had experiences in consulting, 15 years in clinical, and has operated a private practice nutrition counseling office for since 2011. Log in to comment and save this article on your board or send your comments to reviews@supplement-sciences.com

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