Optimal Wellness: The Top Nutrients That Most People Need To Supplement

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Along with providing information on whether these wellness supplements might be right for you, this article also links to Fullscript where you can buy supplements for wellness online through the secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

Nutrition is a cornerstone of overall health, fueling our bodies and supporting vital functions. But in today’s fast-paced life, many of us fall into less-than-perfect dietary habits, often choosing convenience over nutritional value. This trend leads to a gap between what we eat and what our bodies actually need, with diets that might be high in calories but lacking in essential nutrients. Such a disconnect can result in low-level deficiencies in vitamins and minerals, that show up as fatigue, irritability, and poor sleep. Nutritional supplements can bridge this gap, offering a targeted way to ensure our bodies receive the necessary nourishment for optimal wellness but it helps to know where to start.

This article will discuss the top supplements that most people need to start with in order to meet their ideal levels of nutrient intake. These include a quality Multivitamin, Omega-3, Magnesium, and Vitamin D. Look for the Optimal Wellness Protocol button to access ordering for all these products at once from Fullscript.

Where To Start: The Importance of a Multivitamin

The body and each cell within it need more than 40 different nutrients to perform all the necessary functions. A multivitamin combines many vitamins and minerals that are essential for the body’s function. These typically include vitamins like A, C, D, E, and K, along with essential minerals such as calcium, magnesium, zinc, and iron. For greater detail, read our Full Article on Multivitamins. In a nutshell, here are some of the benefits of multivitamin supplements:

  • Filling Nutritional Gaps: Multivitamins help bridge the gap between what we consume and what our bodies need, ensuring that we receive all necessary nutrients.
  • Improving Energy Levels and Reducing Fatigue: By providing essential nutrients, multivitamins can increase energy levels and help fight fatigue.
  • Enhancing Mood and Cognitive Function: Some studies suggest that multivitamins may improve mood and mental clarity by nourishing the brain.
  • Strengthening Immunity: A balanced intake of vitamins and minerals supports the immune system, helping to fend off illnesses.

Who Can Benefit from Multivitamins?

  • Healthy Adults: Foods do not have the nutrients they did 100 years ago when everything was grown slowly in healthy soil and organically. We’re also required to process unprecedented levels of toxins in our air, water, and food. Without a wide array of micronutrients such as those found in a multivitamin, we cannot be confident that adequate levels of these nutrients will be available for these basic cellular processes. Read our article entitled: Detox: An A to Z Guide.
  • Those with Dietary Restrictions: Individuals following specific diets that exclude certain food groups may find multivitamins helpful in maintaining balanced nutrition.
  • People Taking Medications or With Certain Medical Conditions: People with conditions that affect nutrient absorption or those on medications that deplete certain nutrients may benefit from multivitamins.
  • Elderly Populations: As the body ages, nutrient absorption can decrease, and dietary needs may change. Multivitamins can support the nutritional needs of older adults.

Realities of a Less-than-Perfect Diet

The Standard American Diet (SAD) is full of foods that are deficient in essential nutrients. The shift towards processed and convenience foods, along with other dietary habits, has led to a decrease in the consumption of nutrient-dense whole foods. Common deficiencies include vitamins like Vitamin D and B12, minerals like magnesium and iron, and essential fatty acids.

Several factors can affect the body’s ability to absorb these nutrients. Age plays a role as the digestive system’s efficiency can decline with time. Medications can interfere with the body’s ability to break down and absorb specific nutrients. Health conditions, especially those related to the digestive system, can impact nutrient absorption as well. And lifestyle choices, such as excessive alcohol and smoking, can inhibit the body’s ability to process and utilize vital nutrients and increase needs for nutrients.

In light of all these challenges, nutritional supplements can play a crucial role in bridging the gap between what our diets provide and what our bodies actually need. By carefully selecting and incorporating supplements that align with individual nutritional needs, people can enhance their dietary intake. This targeted approach ensures that essential vitamins, minerals, and other nutrients reach adequate levels, compensating for the realities of less-than-perfect dietary habits. It’s a way to support overall health and well-being in an environment where achieving optimal nutrition through diet alone can be challenging.

Order The Best Multivitamin

These are three of the best options for multivitamins, and what makes each one stand out.

O.N.E. Multivitamin by Pure Encapsulations:

  • Methylated forms of B vitamins: Important for people with MTHFR genetic mutation.
  • High level of Vitamin B12: Important for people taking acid-reducing medications or metformin.
  • B6: Important for women who take oral contraceptives that may deplete B6 levels.
  • Zinc: Needed for optimal immune function.
  • Coenzyme Q10: Important in aging, and depleted in statin users.
  • Lutein and Zeaxanthin: Important for eye health.
  • Chromium: Important for anyone with insulin resistance or diabetes. 

Prenatal Vitamins – For Preconception, Nursing Mothers, or Anyone Needing Extra Iron

Prenatal vitamins are designed for pregnancy, pre-conception, and lactating women. This prenatal vitamin has 45 mg of elemental iron, and it is provided in the Bisglycinate form, which should be better tolerated.

Female Athletes and People With Anemia: A prenatal formula might be appropriate for anyone with mild iron deficiency anemia–pregnant or not, because of its high iron levels. The usual go-to supplement for anemia, Ferrous Sulfate at 325 mg typically contains 65 mg of elemental iron with a common side effect of constipation. Prenatal vitamins with the better tolerated bisglycinate form of iron at 45 mg of iron per day may be better tolerated and adequate for people needing extra iron.

Essential Multivitamin by EuroMedica

  • Ginger: Reduces stomach upset.
  • Chromium: Reduces insulin resistance.
  • Vitamin K2: Important for bone health and to reduce cardiovascular risk.
  • Methylated B Vitamins: Important for people with the MTHFR gene mutation.
  • Magnesium: Supports blood pressure and 300+ enzyme functions. Most people have inadequate intake; 150 mg meets 1/3 to 1/2 of adult daily needs.
  • Benfantomine: Prevents thiamine deficiency in people with high alcohol intake.

Omega-3 Fatty Acids: The Brain and Heart Essentials

For people who don’t like fish, it can be challenging to get enough Omega-3. Typical American diets often have an imbalanced Omega-3 to Omega-6 ratio, leaning heavily towards Omega-6. Sometimes the ratio is as imbalanced as 1:15 to 1:20, whereas an ideal ratio might be closer to 1:3 to 1:4. Fish oil supplements, rich in Omega-3 fatty acids, can help correct this imbalance by providing more EPA and DHA, thereby promoting a healthier Omega-3 to Omega-6 ratio and supporting overall wellness.

Omega-3 fatty acids are available in three main types: EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid), and ALA (alpha-linolenic acid). Among these, EPA and DHA are generally considered superior due to their direct role in heart health, brain function, and anti-inflammatory properties. ALA, while beneficial, must be converted into EPA and DHA in the body, a process that is only about 20% efficient.

Natural sources of EPA and DHA include fatty fish like Salmon, Mackerel, Anchovies, Sardines, and Herring (SMASH fish). Krill oil is another excellent source of these essential fats, and for those looking for plant-based options, algal oil serves as a valuable alternative to fish oil. ALA can be found in flaxseeds and walnuts.

Key Benefits Of Omega-3’s:

  • Heart Health: Omega-3s, particularly EPA and DHA, play a significant role in reducing cholesterol and blood pressure, contributing to a healthy heart. They help in regulating heart rhythms and reducing the risk of heart diseases.
  • Brain Function: EPA and DHA are crucial for brain health, particularly in areas like memory enhancement and mood regulation. They are an essential part of the brain’s structure, supporting cognitive function and emotional well-being.
  • Anti-inflammatory Properties: EPA and DHA are known for their anti-inflammatory effects, which can help in managing chronic inflammatory conditions.
  • Promoting Joint Health: These specific fatty acids can ease joint pain and stiffness, supporting overall joint health.
  • Importance for Those Lacking Fish in Their Diet: For individuals who don’t consume fish or have certain dietary restrictions, supplementing with EPA and DHA through sources like krill or algal oil becomes essential to ensure they receive these crucial nutrients.

Omega-3 fatty acids, particularly EPA and DHA, serve as powerful brain and heart boosters. Whether it’s maintaining a healthy heart, enhancing brain function, reducing inflammation, or promoting joint health, the inclusion of these specific nutrients through natural sources or supplements is integral to achieving optimal wellness, especially for those who lack fish in their diet. For a deeper look, read our article: Omega-3: Why Fish Oil Is One of The Most Important Supplements.

Magnesium: The Forgotten Mineral

Magnesium is an essential mineral that plays a fundamental role in our health but is often overlooked. Remarkably, magnesium’s status in the body cannot be accurately judged from the usual serum values, making it challenging to detect deficiencies without specialized nutrient testing. Even though it’s vital for well-being, most people don’t get adequate levels of magnesium from their diet.

A deficiency in magnesium can lead to muscle cramps, irregular heartbeats, fatigue, and a general lack of vitality. These symptoms are not only uncomfortable but can severely impact daily productivity and overall well-being.

Health Benefits of Magnesium:

  • Muscle Function and Relaxation: Magnesium assists in the contraction and relaxation of muscles. Its role as a natural calcium channel blocker helps regulate muscle function, easing muscle cramps, and enhancing overall relaxation.
  • Role in Sleep: Magnesium’s calming effects on the nervous system promote better sleep. Its ability to regulate neurotransmitters that send signals throughout the nervous system aids in relaxation, a key component in healthy sleep patterns.
  • Nerve Function: Magnesium plays a crucial role in transmitting nerve impulses, contributing to mental clarity and focus.

People eating highly processed foods and drinking caffeine are at greater risk of magnesium deficiency. Getting plenty of magnesium through dietary choices or supplementation can improve sleep quality, brain function, muscle function, and vitality by improving the function of 300+ enzyme systems that rely on magnesium as a cofactor. For more details on the benefits of magnesium, and to see more product options, check out our full article: Bridging the Gap: Magnesium Supplements for Better Sleep, Healthier Heart, and More.

Vitamin D: It’s Involved In Everything

Vitamin D is called the sunshine vitamin since we can make it when we’re exposed to sunlight. The problem is that many of us don’t get enough sun exposure. We can also get Vitamin D by eating certain foods. For details, read our Full Article on Vitamin D.

Vitamin D3, the active form of Vitamin D is an essential part of overall health. It supports bone strength, immune function, and mental well-being, and offers protection against chronic diseases.

It’s Particularly in regions with limited sun exposure or among individuals with darker skin tones, ensuring adequate Vitamin D3 through diet or supplementation can be crucial for maintaining optimal health.

Vitamin D deficiency is often referred to as a “silent epidemic,” particularly among people in northern regions and those with darker skin tones. In northern latitudes, where sunlight exposure is limited, especially during winter months, the body’s natural production of Vitamin D can be reduced. This lack of sunlight can lead to a deficiency in Vitamin D, even if a person’s diet includes sources of the vitamin.

Similarly, people with darker skin tones have more melanin, which partially blocks the skin’s ability to produce Vitamin D from sunlight. This factor can contribute to a higher risk of Vitamin D deficiency in these populations. Vitamin D deficiency is a widespread but often unrecognized problem.

The Health Benefits of Vitamin D3

  • Bone Health: Vitamin D plays a vital role in calcium absorption, contributing to the strength and health of bones. This is critical for maintaining bone integrity and preventing conditions like osteoporosis.
  • Immune System Support: Vitamin D3 supports the immune system by helping to fend off infections. This contributes to overall well-being and may reduce the incidence of common illnesses.
  • Mood and Mental Health Regulation: Research has linked Vitamin D3 to improved mood and mental health. It may be beneficial in managing mood disorders and enhancing overall emotional well-being.
  • Potential Protection Against Chronic Diseases: Vitamin D3 has been associated with protection against certain chronic diseases, including heart disease and some cancers. While not a cure, adequate levels can be a part of a strategy for maintaining long-term health.
  • Importance in Regions with Limited Sun Exposure: In areas with limited sunlight, it may be challenging to produce enough Vitamin D3 naturally. Supplements can be a valuable way to ensure adequate levels.
  • Considerations for Those with Darker Skin Tones: Individuals with darker skin tones may have difficulty producing sufficient Vitamin D3 due to the melanin in their skin. Monitoring levels and considering supplementation can be important.

Order Vitamin D

Your Vitamin D supplementation should be based on your lab value and many clinicians point out that the “normal range” minimum of 30 ng/ml is below the optimal range reported in research studies. Vitamin K is included in the product below to help make calcium deposit in bone, rather than in the blood vessels of the heart.

The Value Of Detailed Nutrient Testing

Testing for nutritional deficiencies is available to order directly online through the NutriScape Lab Shop. While most people opt to forego the cost of detailed nutrient testing, there are many situations where testing is far better than guessing.

If a person is searching for relief from health problems, specialty nutrient testing like the NutrEval FMV test can be a crucial tool. This comprehensive analysis uses a first-morning urine sample to provide detailed information on nutrients, amino acids, fatty acids, vitamins, minerals, antioxidants, and organic acids. It provides insights into kidney function and neurotransmitter metabolism. For those struggling with unexplained fatigue, digestive issues, or chronic health conditions, NutrEval FMV can pinpoint nutritional imbalances or deficiencies that might be contributing to those problems. Identifying and addressing these underlying issues can lead to targeted nutritional interventions, providing a pathway to relief and improved overall health.

For those in pursuit of their optimal achievable wellness, NutrEval FMV can be equally valuable. This test offers a deep understanding of an person’s unique nutritional landscape, allowing for a personalized approach to diet and supplementation. Whether it’s an athlete aiming for peak performance, an older adult taking medication and looking to support aging gracefully, or anyone desiring to maintain a vibrant, healthy life, NutrEval FMV can guide personalized wellness strategies. By identifying specific nutritional needs, this test helps to create a tailored plan that supports individual goals, enhances well-being, and helps a person achieve their optimal level of wellness.

Are These Vitamins For Optimal Wellness Safe?

Multivitamins, omega-3 fish oil, magnesium, and Vitamin D are recognized as safe supplements when used according to recommended guidelines. Multivitamins are widely used to ensure an adequate intake of essential nutrients and typically do not cause adverse effects when taken as directed. Omega-3 fish oil supplements, known for their cardiovascular benefits, are considered safe and are well-tolerated by most individuals. Magnesium, important for various bodily functions, is safe for most people, although it’s always advisable to adhere to the recommended dosage to avoid any potential side effects like digestive upset. Vitamin D, crucial for bone health and immune function, is also safe when taken within recommended levels.

Medication Interactions with Wellness Supplements

  • Blood Thinners (e.g., Warfarin): May interact with vitamin K in multivitamins, affecting blood clotting. Omega-3s can increase bleeding risk when taken with these medications
  • Antacids and Acid-Blocking Drugs: Can reduce the absorption of certain minerals and vitamins in multivitamins.
  • Osteoporosis Medications (Bisphosphonates): Magnesium can interfere with the absorption of these drugs.
  • Blood Pressure Medications: Omega-3 supplements can lower blood pressure, potentially enhancing the effects of these drugs.
  • Diuretics: Some diuretics can increase the excretion of magnesium, leading to a deficiency.
  • Antibiotics (e.g., Tetracycline, Quinolone): Magnesium can reduce the effectiveness of these antibiotics by binding to them.
  • Steroids (e.g., Prednisone): Can reduce calcium absorption, countering the effects of Vitamin D and therefore increasing calcium and vitamin D needs.
  • Weight Loss Drugs (e.g., Orlistat): These drugs can reduce the absorption of Vitamin D.
  • Certain Seizure Medications (e.g., Phenobarbital, Phenytoin): May affect Vitamin D metabolism and reduce its effectiveness.

Medical Conditions: When To Get Guidance

Supplements aren’t always safe for everyone. Health conditions such as cancer, kidney disease, and liver conditions like Cirrhosis or Non-Alcoholic Fatty Liver Disease (NAFLD) require a specialized understanding of nutritional needs, potential medication interactions, and individual tolerances. Supplement safety answers may be available from your physician or pharmacist, but for wider advice on how nutritional supplements can work with your overall nutrition and medical picture, it pays to seek out a Registered Dietitian specializing in the management of the your medical condition.

Why Professionals Choose the Fullscript Formulary

Your health is on the line. Health professionals know that many other online and retail options set a very low bar for quality–sometimes amazingly low. The Fullscript formulary is the most secure online source for the highest quality brands securely sourced to assure freshness and purity. Here’s what makes Fullscript the best:

  • Meticulous vetting of brand quality. Health professionals trust Fullscript to continuously monitor the quality of each item on the platform. Other retailers operate with profit as their highest or only motive when choosing brands. Fullscript cares only about quality and reliability. Unlike discount stores, large online marketplaces, and other retailers you won’t find ingredients sourced from China or other questionable locations or companies.
  • Always 20% Discount off the manufacturer’s retail price. When you follow any link from Supplement-Sciences.com, you will automatically get 20% off the retail price.
  • Free shipping over $50.
  • Freshness. Fullscript prioritizes freshness over bulk buying even if it means an increased risk of briefly being out of stock.
  • Top quality phone and online support. When you call, knowledgeable humans at Fullscript answer your questions.
  • How It Works:
    • Easy Sign-up & No Spam Email: Click the “View Product” button below to be taken to Fullscript’s login page where you can quickly create your secure account with just your name, email, and phone number. Then you will be taken directly to the product page.
    • Wide variety of supplement options: Once you sign in to your account, you are not limited to the products listed below. You will see similar items listed at the bottom of each product page on Fullscript.
    • Search For What You Want: Once inside Fullscript, you can search for the exact brands and products you want from their wide selection of quality brands.

To Sum It Up

Nutritional supplementation can’t reverse all the negative health effects of unhealthy food choices–no one would claim that it does. But nutritional supplementation has a vital role to play in today’s world where modern diets often fall short of essential nutrients, and factors such as age, medication, and health conditions can affect nutrient absorption.

This article has limited its focus to supplements for the most common nutritional deficiencies. Incorporating multivitamins, Vitamin D when needed, Omega-3 for those not eating fish, and Magnesium for people with intake can provide key health benefits, supporting everything from heart health and cognitive function to mood regulation and joint comfort.

For those who want to test instead of guessing at their nutrient status, tools like the NutrEval offer an insightful glimpse into specific nutrient deficiencies, allowing for a more targeted and personalized approach to supplementation. By understanding our unique nutritional needs and filling the gaps with the right foods and supplements, we can take control of our health journey.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


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Supplement Sciences

Staff Authors at Nutriscape have been working on this article and it is still a work in progress. Please feel free to login and comment on what you see so far.

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