Lysine’s Role in Clear Skin, Stress Reduction, and Strong Immunity

Secure Ordering | Free Shipping | Best Quality | Best Prices

Along with providing information on whether lysine supplements might be right for you, this article also links to Fullscript where you can buy high quality supplements. Order online through Fullscript’s secure healthcare formulary to get the best prices and free shipping on professional-grade supplements.

Lysine is an essential amino acid that plays a key role in supporting overall health. Since the body cannot produce lysine on its own, it must be obtained through diet or supplements. This nutrient contributes to protein synthesis, supports immune function, and assists in collagen production, making it important for tissue repair and skin health. Some people use lysine supplements to help manage cold sores and promote general wellness. In this article, we break down the science behind lysine and explain why you might want to consider adding it to your diet.

What is Lysine

Lysine is an essential amino acid your body needs but can’t make on its own, so it has to come from food or supplements. It plays a key role in building proteins, which help your body grow, repair tissues, and stay strong. Lysine also supports collagen production, the protein that keeps your skin firm, helps wounds heal, and keeps your joints flexible.

Beyond its role in keeping tissues healthy, lysine helps your body absorb calcium, which is important for strong bones and teeth. It also plays a part in immune health by supporting the production of enzymes and antibodies that help protect your body from infections. Some people take lysine supplements to help manage cold sores, as it may slow down how the herpes simplex virus replicates.

You can find lysine naturally in foods like meat, poultry, fish, eggs, and dairy products. Plant-based options include lentils, quinoa, and pumpkin seeds. People who don’t get enough lysine from their diet or have higher protein needs sometimes use supplements to support skin health, bone strength, or immune function.

What are the Health Benefits of Lysine

  • Supports Muscle Growth: Lysine helps in the production of protein, which is crucial for muscle development and repair. [PMID: 33290094]
  • Enhances Calcium Absorption: Lysine can improve how well your body absorbs calcium, which is essential for bone health. In a study, researchers looked at the effects of taking L-lysine (800 mg per day) on calcium absorption in 45 patients with osteoporosis. They found that L-lysine significantly improved calcium absorption. /PMID: 1486246
  • Promotes Skin Health: Lysine aids in the formation of collagen, a protein that helps keep your skin firm and healthy. [PMID: 18373252]
  • Boosts Immune System: Lysine has shown promise in improving immune response, making it easier for your body to fight viruses and bacteria. Lysine has shown promise in enhancing the immune response, making it easier for your body to fight viruses and bacteria. Researchers studied the effects of L-lysine and L-arginine and found that they improved neutrophils and increased specific lymphocytes. This combination could enhance the immune response, making it useful for treating infections and supporting the immune system. /PMID: 7555612
  • Manages Anxiety: Some studies suggest that lysine can help manage anxiety by blocking stress-related receptors. In a 3-month study, researchers found that lysine-fortified wheat reduced stress levels during a blood test in women and showed fewer physical signs of stress in men. /PMC420386
  • Improves Wound Healing: Lysine can speed up the healing process by helping create new tissue at the site of a wound. In a study, researchers gave L-lysine to an 11-year-old and noticed an improvement in Pityriasis Rosea; new scaly patches stopped appearing. /PMID: 33326128
  • Reduces Cold Sores: Lysine may help prevent or lessen the severity of cold sores caused by the herpes simplex virus. A small study found that taking more than 3 grams a day might help reduce how often the sores come back and improve symptoms, but further research is needed. /PMC6419779
  • Helps in Hormone Production: Lysine is involved in creating hormones, enzymes, and antibodies that support bodily functions. Research has shown that taking 1200 mg of L-lysine together with 1200 mg of L-arginine prompts the body to release growth hormone and insulin. This effect was reliably observed, and the growth hormone produced was active and effective. /PMID: 6790230

How Much Lysine Do We Need Each Day?

There are no Recommended Dietary Allowances (RDAs) for lysine, but adults are estimated to need about 38 mg per kilogram per day. This works out to about 2200-3800 mg for men or 1900-3000 mg per day for women.

Lysine is an essential amino acid, which means your body can’t make it and you need to get it from food or supplements.

Food Sources of Lysine

Lysine is an amino acid building block of protein and therefore you can get it from foods that are rich in protein.

Food SourceLysine Amount Per Serving (mg)
Chicken breast2,500
Tofu (1 cup)700
Lentils (1 cup)1,000
Eggs (1 large)600
Salmon (3 oz)1,500
Beef steak (3 oz)2,100
Parmesan cheese (1 oz)900
Quinoa (1 cup)440
Pumpkin seeds (1 oz)360
Almonds (1 oz)300
Note that these values are approximate and can vary based on factors like preparation method and specific brand.

Who Might Want to Supplement with Lysine?

Lysine supplements are not for most people who eat a varied diet with plenty of protein, but here are a few situations where a lysine supplement might be helpful:

  • Cold Sores: If you frequently get cold sores, lysine supplements may help reduce their occurrence or severity.
  • Vegetarian or Vegan Diet: If your diet lacks animal proteins, you might need lysine supplements to get this essential amino acid.
  • Athletic Performance: Athletes sometimes use lysine for muscle recovery and to reduce fatigue.
  • Skin Health: People with certain skin conditions might take lysine supplements to improve overall skin health.
  • Bone Strength: Lysine helps with calcium absorption, making it useful for people looking to improve bone health.

Are Lysine Supplements Safe?

You’ll find lysine naturally in foods like meat, fish, and dairy. Because it comes from these common sources, it’s safe for most people when taken in appropriate amounts. Lysine supplements are safe for most people when taken in recommended doses. High doses of lysine can cause digestive side effects. Overall, lysine supplements are a well-tolerated option for those looking to increase their intake of this essential amino acid.

What Medications Interact with Lysine

  • Aminoglycoside Antibiotics (e.g., gentamicin): Interaction is more likely if lysine supplements and antibiotics are taken at the same time, potentially increasing the risk of side effects like kidney damage.
  • Diuretics: Taking lysine supplements generally can interfere with certain water pills, affecting potassium levels in the body.
  • Blood Pressure Medications: Interaction may occur if lysine supplements are taken at the same time, potentially leading to changes in blood pressure.
  • Antiviral Medications: Taking lysine supplements generally could alter the efficacy of some antiviral medications.
  • Osteoporosis Medications (e.g., bisphosphonates): Interaction is more likely if taken at the same time as lysine supplements, affecting calcium levels in the body.

Supplement Interactions with Lysine

  • Calcium: Interaction is likely when taking lysine supplements generally, as lysine increases calcium absorption, potentially leading to elevated calcium levels.
  • Magnesium: Interaction occurs if lysine and magnesium supplements are taken at the same time, affecting the absorption of both.
  • Zinc: Similar to magnesium, the interaction happens if lysine and zinc are taken at the same time, impacting the absorption of both.
  • Arginine: Taking lysine and arginine supplements at the same time may reduce the effectiveness of each, as they share the same pathways in the body.
  • Herbal Diuretics (e.g., dandelion, horsetail): Taking lysine supplements generally can interact with herbal diuretics, affecting mineral balance and hydration levels.
  • Selenium: Interaction is likely if lysine supplements and selenium are taken at the same time, as lysine might lower how much selenium the body absorbs.

Order Lysine Online

Why Professionals Choose the Fullscript Formulary

Health professionals know that many online and retail options set a very low bar for quality– sometimes amazingly low. The Fullscript formulary is the most secure online source for the highest quality brands, securely sourced to assure freshness and purity. Here’s what makes Fullscript the best:

  • Meticulous vetting of brand quality. Meticulous vetting of brand quality. Health professionals trust Fullscript to monitor the quality of every item. While other retailers prioritize profit above all else, Fullscript focuses solely on quality and reliability. Unlike discount stores and large online marketplaces, you won’t find ingredients sourced from China or other questionable suppliers.
  • Free shipping over $50 and best prices when you order through Supplement Sciences.
  • Wide Selection: Access to the entire Fullscript formulary. Search for the exact brands and products you want.
  • Easy Sign-up & No Spam Email: Click “View Product” or the button below to be taken to Fullscript’s login page where you can quickly create your secure account with just your name, email, and phone number. Then you will be taken directly to the product page.

Lysine 500 mg by Thorne76584

Manufacturer description: Lysine is an essential amino acid that your body doesn’t produce on its own, which means it must come from diet or supplementation. Primary dietary sources of lysine are meat, poultry, fish, dairy, tofu, lentils, and beans. However, because many individuals don’t get enough lysine through diet alone, supplementation of this essential amino acid is advisable.

Thorne’s Lysine uses the purest, most absorbable form of this amino acid – without adding unnecessary additives or preservatives.

Health benefits of lysine include:

  • Wound healing – Lysine is often recommended for supporting the healing of sores and wounds because of its benefits to collagen formation and immune function.*
  • Some evidence indicates lysine can be beneficial for maintaining healthy gum and lip tissues.*
  • Promotes immune health – lysine provides nutritional support to help your body maintain its natural defenses.*
  • Skin health – This amino acid is known to promote collagen formation, which in turn benefits the health and elasticity of skin.*
  • Bone Health – lysine promotes calcium absorption, which is needed to maintain strong bones and teeth.*
    Suggested Use: Take 1 capsule two to three times daily or as recommended by your health professional.

Amount Per 1 Capsule Serving
L-Lysine
 … 500mg (as L-Lysine Monohydrochloride)


L-Lysine Powder by NOW Foods69095

Manufacturer description: L-Lysine is an essential amino acid that must be obtained through the diet or through supplementation.* Lysine is necessary for the production of all proteins in the body, and is required for the maintenance of the structural proteins collagen and elastin, which form all connective tissue such as skin, tendon, and bone.* L-Lysine is also a precursor to L-carnitine, which is needed for fat metabolism and energy production.* In addition, L-Lysine may help to support a healthy immune system and proper cardiovascular function.*

  • Pure Powder
  • Supports Collagen Synthesis*
  • Healthy Immune Function*

Suggested Use: Take 1/4 level teaspoon daily.

Serving Size: ¼ Level Teaspoon (appx 552mg)

Amount Per Serving

L-Lysine … 435mg* (from L-Lysine Hydrochloride)


Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Food is one of the “Pillars of Health”. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Lysine supplements offer several health benefits such as supporting immune function, promoting skin health, and aiding in calcium absorption for stronger bones. While generally safe, it’s important to note that lysine can interact with certain medications and other supplements. Understanding these interactions and knowing your needs can help you make informed choices about incorporating lysine into your wellness routine.


This Article is Not a Substitute for Medical Advice

This information is provided for educational purposes only and is not a substitute for medical advice. Supplement Sciences does not provide medical care and cannot ensure the safety or effectiveness of any product for your personal use. Always consult your physician before starting any supplement, especially if you are pregnant, breastfeeding, or managing a serious health condition such as cancer, liver disease, or kidney disease. Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease.


UNREVISED DRAFT

Secure Ordering | Free Shipping | Best Quality | Best Prices

Along with providing information on whether lysine supplements might be right for you, this article also links to Fullscript where you can buy high quality supplements. Order online through Fullscript’s secure healthcare formulary to get the best prices and free shipping on professional-grade supplements.

Lysine is an essential amino acid that the body needs but can’t make on its own. It has to come from food or supplements. Lysine helps with building proteins, supports the immune system, and is involved in making collagen, which is important for skin and tissue repair. Some people take lysine supplements to help manage cold sores or to support overall health. This article looks at what lysine does in the body and why it might be useful to include in your routine.

What is Lysine

Lysine is an amino acid the body needs but can’t make on its own, so it has to come from food or supplements. It plays a role in building proteins that help with growth, tissue repair, and maintaining strength. Lysine also supports collagen production, which is important for skin, wound healing, and keeping joints flexible.

It also helps the body absorb calcium, which supports bone and dental health. Lysine plays a part in the immune system by helping produce enzymes and antibodies that defend against infection. Some people take lysine supplements to manage cold sores, as it may interfere with the way the herpes virus replicates.

Lysine is found in foods such as meat, poultry, fish, eggs, and dairy. Plant-based sources include lentils, quinoa, and pumpkin seeds. People who eat limited protein or have higher needs may choose supplements to support areas like skin, bones, or immune health.

What are the Health Benefits of Lysine

  • Supports Muscle Growth: Lysine helps in the production of protein, which is crucial for muscle development and repair. [PMID: 33290094]
  • Enhances Calcium Absorption: Lysine can improve how well your body absorbs calcium, which is essential for bone health. In a study, researchers looked at the effects of taking L-lysine (800 mg per day) on calcium absorption in 45 patients with osteoporosis. They found that L-lysine significantly improved calcium absorption. /PMID: 1486246
  • Promotes Skin Health: Lysine aids in the formation of collagen, a protein that helps keep your skin firm and healthy. [PMID: 18373252]
  • Boosts Immune System: Lysine has shown promise in improving immune response, making it easier for your body to fight viruses and bacteria. Lysine has shown promise in enhancing the immune response, making it easier for your body to fight viruses and bacteria. Researchers studied the effects of L-lysine and L-arginine and found that they improved neutrophils and increased specific lymphocytes. This combination could enhance the immune response, making it useful for treating infections and supporting the immune system. /PMID: 7555612
  • Manages Anxiety: Some studies suggest that lysine can help manage anxiety by blocking stress-related receptors. In a 3-month study, researchers found that lysine-fortified wheat reduced stress levels during a blood test in women and showed fewer physical signs of stress in men. /PMC420386
  • Improves Wound Healing: Lysine can speed up the healing process by helping create new tissue at the site of a wound. In a study, researchers gave L-lysine to an 11-year-old and noticed an improvement in Pityriasis Rosea; new scaly patches stopped appearing. /PMID: 33326128
  • Reduces Cold Sores: Lysine may help prevent or lessen the severity of cold sores caused by the herpes simplex virus. A small study found that taking more than 3 grams a day might help reduce how often the sores come back and improve symptoms, but further research is needed. /PMC6419779
  • Helps in Hormone Production: Lysine is involved in creating hormones, enzymes, and antibodies that support bodily functions. Research has shown that taking 1200 mg of L-lysine together with 1200 mg of L-arginine prompts the body to release growth hormone and insulin. This effect was reliably observed, and the growth hormone produced was active and effective. /PMID: 6790230

How Much Lysine Do We Need Each Day?

There’s no official Recommended Dietary Allowance (RDA) for lysine, but estimates suggest that adults need about 38 mg per kilogram of body weight each day. For most men, that comes to around 2200 to 3800 mg daily. For women, it’s about 1900 to 3000 mg.

Since lysine is an essential amino acid, the body can’t produce it on its own. It has to come from food or supplements.

Food Sources of Lysine

Lysine is an amino acid building block of protein and therefore you can get it from foods that are rich in protein.

Food SourceLysine Amount Per Serving (mg)
Chicken breast2,500
Tofu (1 cup)700
Lentils (1 cup)1,000
Eggs (1 large)600
Salmon (3 oz)1,500
Beef steak (3 oz)2,100
Parmesan cheese (1 oz)900
Quinoa (1 cup)440
Pumpkin seeds (1 oz)360
Almonds (1 oz)300
Note that these values are approximate and can vary based on factors like preparation method and specific brand.

Who Might Want to Supplement with Lysine?

Most people who eat a varied diet with enough protein get plenty of lysine, so supplements aren’t usually necessary. However, there are some situations where a lysine supplement might be useful:

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  • Cold Sores: If you frequently get cold sores, lysine supplements may help reduce their occurrence or severity.
  • Vegetarian or Vegan Diet: If your diet lacks animal proteins, you might need lysine supplements to get this essential amino acid.
  • Athletic Performance: Athletes sometimes use lysine for muscle recovery and to reduce fatigue.
  • Skin Health: People with certain skin conditions might take lysine supplements to improve overall skin health.
  • Bone Strength: Lysine helps with calcium absorption, making it useful for people looking to improve bone health.

Are Lysine Supplements Safe?

Lysine is found naturally in foods like meat, fish, and dairy. Since these are common in many diets, most people get enough without any issues. When taken in usual amounts, lysine supplements are generally well tolerated. Taking too much may lead to digestive discomfort. For those who need more lysine, supplements can be a practical way to meet their needs.

What Medications Interact with Lysine

  • Aminoglycoside antibiotics (such as gentamicin): Taking lysine supplements at the same time may raise the risk of side effects like kidney stress.
  • Diuretics: Lysine may interact with certain water pills and influence how the body manages potassium.
  • Blood pressure medications: Using lysine with these drugs may affect blood pressure control.
  • Antiviral medications: Lysine might change how some antiviral drugs work in the body.
  • Osteoporosis medications (like bisphosphonates): Taking lysine at the same time may affect how the body handles calcium.

Supplement Interactions with Lysine

  • Calcium: Lysine can help the body absorb more calcium, which may lead to higher calcium levels when taken together.
  • Magnesium: Taking lysine and magnesium at the same time may affect how well each is absorbed.
  • Zinc: Similar to magnesium, combining lysine with zinc may reduce how much of each the body takes in.
  • Arginine: These two amino acids use the same transport system in the body, so taking them together may lower how well each one works.
  • Herbal diuretics (like dandelion or horsetail): Lysine may affect how these herbs influence mineral levels and hydration.
  • Selenium: Lysine might reduce how much selenium the body absorbs when taken at the same time.

Order Lysine Online

Why Professionals Choose the Fullscript Formulary

Health professionals know that many online and retail options set a very low bar for quality– sometimes amazingly low. The Fullscript formulary is the most secure online source for the highest quality brands, securely sourced to assure freshness and purity. Here’s what makes Fullscript the best:

  • Meticulous vetting of brand quality. Meticulous vetting of brand quality. Health professionals trust Fullscript to monitor the quality of every item. While other retailers prioritize profit above all else, Fullscript focuses solely on quality and reliability. Unlike discount stores and large online marketplaces, you won’t find ingredients sourced from China or other questionable suppliers.
  • Free shipping over $50 and best prices when you order through Supplement Sciences.
  • Wide Selection: Access to the entire Fullscript formulary. Search for the exact brands and products you want.
  • Easy Sign-up & No Spam Email: Click “View Product” or the button below to be taken to Fullscript’s login page where you can quickly create your secure account with just your name, email, and phone number. Then you will be taken directly to the product page.

Lysine 500 mg by Thorne76584

Manufacturer description: Lysine is an essential amino acid that your body doesn’t produce on its own, which means it must come from diet or supplementation. Primary dietary sources of lysine are meat, poultry, fish, dairy, tofu, lentils, and beans. However, because many individuals don’t get enough lysine through diet alone, supplementation of this essential amino acid is advisable.

Thorne’s Lysine uses the purest, most absorbable form of this amino acid – without adding unnecessary additives or preservatives.

Health benefits of lysine include:

  • Wound healing – Lysine is often recommended for supporting the healing of sores and wounds because of its benefits to collagen formation and immune function.*
  • Some evidence indicates lysine can be beneficial for maintaining healthy gum and lip tissues.*
  • Promotes immune health – lysine provides nutritional support to help your body maintain its natural defenses.*
  • Skin health – This amino acid is known to promote collagen formation, which in turn benefits the health and elasticity of skin.*
  • Bone Health – lysine promotes calcium absorption, which is needed to maintain strong bones and teeth.*
    Suggested Use: Take 1 capsule two to three times daily or as recommended by your health professional.

Amount Per 1 Capsule Serving
L-Lysine
 … 500mg (as L-Lysine Monohydrochloride)


L-Lysine Powder by NOW Foods69095

Manufacturer description: L-Lysine is an essential amino acid that must be obtained through the diet or through supplementation.* Lysine is necessary for the production of all proteins in the body, and is required for the maintenance of the structural proteins collagen and elastin, which form all connective tissue such as skin, tendon, and bone.* L-Lysine is also a precursor to L-carnitine, which is needed for fat metabolism and energy production.* In addition, L-Lysine may help to support a healthy immune system and proper cardiovascular function.*

  • Pure Powder
  • Supports Collagen Synthesis*
  • Healthy Immune Function*

Suggested Use: Take 1/4 level teaspoon daily.

Serving Size: ¼ Level Teaspoon (appx 552mg)

Amount Per Serving

L-Lysine … 435mg* (from L-Lysine Hydrochloride)


Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Food is one of the “Pillars of Health”. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Lysine supplements may support the immune system, help maintain healthy skin, and assist with calcium absorption, which is important for bone health. While they are usually well tolerated, lysine can interact with some medications and other supplements. Being aware of these interactions and understanding your own needs can help you decide whether adding lysine makes sense for you.


This Article is Not a Substitute for Medical Advice

This information is provided for educational purposes only and is not a substitute for medical advice. Supplement Sciences does not provide medical care and cannot ensure the safety or effectiveness of any product for your personal use. Always consult your physician before starting any supplement, especially if you are pregnant, breastfeeding, or managing a serious health condition such as cancer, liver disease, or kidney disease. Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease.


About the Author

Supplement Sciences

This article is created by the Supplement Sciences writing team. It is reviewed for medical and nutritional accuracy by Stephanie Figon, MS, RDN, LD. Please let us know your thoughts by messaging us at reviews@supplement-sciences.com.

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