Ginko Biloba: The Real Story From Better Memory to Lower Stress

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Ginkgo Biloba, a supplement made from the leaves of one of the oldest tree species on Earth, has piqued the interest of scientists and health enthusiasts alike. This natural remedy offers a variety of benefits, such as enhancing memory and focus, reducing symptoms of anxiety, and improving blood circulation. In this article, we’ll dive into the science behind these claims to give you a clearer understanding of what Ginkgo Biloba can do for you.

What Is Ginko Biloba?

Ginkgo Biloba is a natural supplement made from the leaves of the ginkgo tree, which has been around for more than 270 million years. Native to China, the ginkgo tree is one of the oldest living tree species in the world. The leaves contain compounds that have a range of health benefits. Often consumed in pill, capsule, or extract form, Ginkgo Biloba has made a name for itself primarily as a brain booster. But that’s not all it has to offer; the supplement is also known for improving blood circulation and reducing symptoms of anxiety.

What Are the Benefits of Ginko Biloba?

  • Improves Memory and Focus: Studies show that Ginkgo Biloba can improve cognitive function, making tasks like remembering names or focusing on work easier. [PMID: 21170694]
  • Reduces Anxiety Symptoms: Researchers state that Ginkgo biloba has been shown, “to improve cognitive abilities in impaired individuals and reduce anxiety under pathological conditions.” [PMID: 27908257]
  • Enhances Blood Circulation: Ginkgo Biloba helps widen blood vessels, which can improve blood flow to various parts of the body, including the brain. Ginkgo biloba extract can improve brain’s oxygen supply. [PMID: 25847559]
  • Helps Fight Inflammation: Anti-inflammatory properties in Ginkgo Biloba make it useful for reducing symptoms related to inflammatory conditions. [PMID: 35781715]
  • Protects Vision and Eye Health: Antioxidants in Ginkgo Biloba can help protect the eyes from age-related deterioration. [PMC7299225]
  • Supports Respiratory Health: Some people use Ginkgo Biloba to help treat asthma symptoms and improve overall lung function. [PMID: 30945705]
  • Relieves Menstrual Pain: There is evidence to suggest that Ginkgo Biloba can alleviate symptoms of PMS [PMID: 19678774] and the severity of menstrual cramps. [PMC10472015]
  • Boosts Antioxidant Levels: The plant contains high levels of flavonoids and terpenoids, antioxidants that provide several health benefits.
  • Depression: Ginko was found to be an effective add-on treatment for elderly people with depression. [PMC6181482]

In humans, the positive effects were shown in diabetes, metabolic syndrome, and ischemic colitis. These effects are due to the presence of compounds such as bilobalide, isoramnetina, quercetin, kaempferol, and ginkgolides A, B, and C. For these reasons, Ginko Biloba can be a low-cost alternative to the therapeutic approach of several pathologies since it acts in the prevention, treatment, and inhibition of several complications of common comorbidities.

Effects of Ginkgo biloba on Diseases Related to Oxidative Stress [PMID: 32097975]

Is Ginko Biloba Safe?

Ginkgo biloba supplements have a long history of use and are generally considered safe for most people when used as directed. They are derived from the leaves of the ginkgo tree and have been used in traditional medicine for various purposes. Numerous clinical studies and reviews have reported minimal adverse effects associated with ginkgo biloba supplementation, with the most common being mild digestive issues.

Medication Interactions with Ginko Biloba

  • Blood Thinners: Such as warfarin and aspirin, as Ginkgo can enhance their blood-thinning effects.
  • Antidepressants: Including selective serotonin reuptake inhibitors (SSRIs) like fluoxetine and sertraline, as it may alter their effectiveness.
  • Anticonvulsants: Like carbamazepine, since Ginkgo might lower their efficacy in controlling seizures.
  • Blood Pressure Medication: Ginkgo can affect blood pressure levels, potentially interfering with medications like diuretics or beta-blockers.
  • Diabetes Medication: Ginkgo may alter blood sugar levels, so it could interfere with insulin or oral hypoglycemics.
  • Antiplatelet/Anticoagulant Drugs: Such as clopidogrel, which might have their effects amplified by Ginkgo.
  • Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Including ibuprofen and naproxen, as Ginkgo can heighten the risk of bleeding.
  • MAOIs (Monoamine Oxidase Inhibitors): Ginkgo might interact with these antidepressants, possibly leading to hazardous effects.

Supplement Interactions with Ginko Biloba

  • Garlic: Both have blood-thinning properties, so taking them together might increase the risk of bleeding.
  • Ginseng: This supplement can also affect blood clotting, so combining it with Ginkgo could amplify this effect.
  • St. John’s Wort: Known to interact with a variety of medications, St. John’s Wort may also have interactions with Ginkgo, particularly when it comes to altering neurotransmitter levels.
  • Omega-3 Fatty Acids: Like Ginkgo, these have blood-thinning effects and may increase the risk of bleeding when taken together.
  • Vitamin E: Also a blood-thinner, combining this vitamin with Ginkgo might elevate the risk of bleeding.
  • Saw Palmetto: This supplement may have blood-thinning properties, which could be enhanced when taken with Ginkgo.
  • Coenzyme Q10 (CoQ10): Both supplements can affect blood clotting, so taking them together could compound this effect.

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Ginkgo Biloba 120mg + Gotu Kola + Siberian Ginseng by Protocol for Life Balance

Ginkgo Biloba 120mg/24% Plus 100c is available by Protocol.

-24% / 6% Standardized Extract
-with Gotu Kola & Eleuthero
-A Dietary Supplement
-Vegetarian Formula

Ginkgo Biloba is grown and extracted under the highest quality standards and is standardized to min. 24% ginkgoflavonglycosides and min. 6% Terpene Lactones, including Ginkgolide B, the most significant fraction, and Ginkgolides A, C and Bilobalide. Ginkgo helps to promote optimal circulation and healthy cognitive function, while providing antioxidant protection against free-radical destruction.* This award winning formula includes Eleuthero (Eleutherococcus senticosus) and Gotu Kola (Centella asiatica).

Brain/Cognitive Support.

Suggested Use:
As a dietary supplement, take 1 Vcap® 1 to 2 times daily, preferably with meals or as directed by your healthcare practitioner

Serving Size: 1 Vcap®

Amount Per Serving
Ginkgo Biloba Extract …
 120mg
(Leaf)(50:1 Standardized Extract, containing min. 24% Ginkgoflavonglycosides and 6% Terpene Lactones)
Gotu Kola … 150mg
(Centella asiatica)(Leaf)
Eleuthero … 125mg
(Eleutherococcus senticosus)(Root)

Ginkgo 50 160mg by Pure Encapsulations

50:1 extract, contains 24% ginkgoheterosides and 6% terpene lactones; helps with mild memory problems associated with aging; improves absentmindedness

*The Ginkgo tree has long been utilized for long and healthy life; for centuries, Chinese and Japanese traditions have used ginkgo leaves to support the brain, heart, and lungs. The active components of Ginkgo biloba, ginkgoheterosides and terpene lactones, enhance the flow of oxygen and blood to the brain and improve transmission of nerve impulses, supporting mental acuity. Ginkgo biloba offers nutritional support to the vascular system by sustaining the strength and elasticity of blood vessels and capillaries. In addition, it maintains healthy platelet function and acts as a free radical scavenger. Ginkgo 50 extract offers enhanced Ginkgo biloba support, providing 24% ginkgoheterosides and 6% terpene lactones per capsule.

Ginkgo biloba provides time-tested nutritional support for circulation and mental acuity.

Take 1–2 capsules per day, in divided doses, between meals.

Serving Size: 1 vegetable capsule

Amount Per Serving
ginkgo extract
 … 160mg
(ginkgo biloba)(leaf)
(standardized to contain 24% ginkgoheterosides and 6% terpene lactones)

To Sum It Up

Ginkgo Biloba offers an array of health benefits, from improving memory and focus to enhancing blood circulation. It also shows promise in reducing anxiety symptoms and fighting inflammation. While the science behind these benefits continues to evolve, the supplement remains a popular choice for those looking to support various aspects of their well-being.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


About the Author

Stephanie Figon, MS, RDN, LD

Creator of Supplement Sciences and NutriScape.NET. As a dietitian since 1992, Steph has had experiences in consulting, 15 years in clinical, and has operated a private practice nutrition counseling office for since 2011. Log in to comment and save this article on your board or send your comments to reviews@supplement-sciences.com

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