Feverfew: A Traditional Approach for Allergies, Migraines, and More

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Feverfew has piqued the interest of the medical and scientific community for its potential health benefits. Rich in compounds like parthenolide, feverfew supplements have been explored for their effectiveness in various health-related applications. This article aims to provide a comprehensive overview of feverfew, detailing its active ingredients, the mechanism behind its effects, and what current research says about its potential benefits and considerations for use.

What Is Feverfew?

Feverfew, known scientifically as Tanacetum parthenium, is a medicinal herb known for its therapeutic benefits, tracing back to traditional European medicine. It is primarily recognized for its effectiveness in treating fever, migraines, and tension headaches, thanks to its active compounds such as parthenolide, which plays a key role in its anti-inflammatory and pain-relieving properties, and flavonoids, known for their antioxidant benefits. The plant’s leaves, either dried or fresh, are used in making supplements that many find beneficial for not just headaches but also conditions like arthritis due to its anti-inflammatory effects. Emerging research hints at feverfew’s broader health potentials, including reducing inflammation and possibly aiding in cancer prevention.

What Are the Benefits of Feverfew?

  • Migraine and Headache Relief: Feverfew supplements are commonly used to alleviate migraine and tension headaches.
  • Anti-inflammatory Properties: The active compounds in feverfew, such as parthenolide, exhibit anti-inflammatory effects that may help reduce pain and inflammation in various conditions.
  • Antioxidant Support: Feverfew contains flavonoids and other antioxidants that can help combat oxidative stress and protect cells from damage caused by free radicals.
  • Arthritis Management: Some studies suggest that feverfew may have the potential to manage symptoms of arthritis, including pain and inflammation.
  • Menstrual Discomfort: Feverfew supplements may offer relief from menstrual cramps and discomfort due to its anti-inflammatory properties.
  • Skin Health: Preliminary research indicates that feverfew may have benefits for skin health, possibly helping to soothe irritation and reduce inflammation.
  • Natural Fever Reducer: Traditionally, feverfew has been used to lower fever, although more research is needed to fully understand its effectiveness for this purpose.
  • Digestive Health: Feverfew’s anti-inflammatory properties may help alleviate symptoms of digestive disorders such as indigestion, bloating, and stomach discomfort.
  • Allergy Relief: Research suggests that feverfew could reduce allergic reactions and symptoms like sneezing, runny nose, and itchy eyes, offering relief for allergy sufferers.
  • Stress and Anxiety Reduction: Feverfew’s calming effects on the nervous system may contribute to reducing stress and anxiety levels, promoting a sense of calm and relaxation.
  • Improved Sleep: Feverfew’s calming properties could lead to better sleep quality and help alleviate insomnia or sleep disturbances for a more restful night.
  • Immune Support: The antioxidants and anti-inflammatory compounds in feverfew might strengthen the immune system, supporting overall immune function and helping the body fight off infections.
  • Cardiovascular Health: Early studies suggest that feverfew may benefit heart health by reducing blood pressure and improving circulation, which might lower the risk of heart disease.
  • Cancer Prevention: Preliminary research indicates that feverfew may possess anticancer properties, possibly aiding in the prevention or slowing down the growth of certain types of cancer cells.

Is Feverfew Safe?

Feverfew is safe for most people when used appropriately and in recommended doses. However, it’s essential to exercise caution, especially when considering its use in certain populations or alongside other medications. Mild side effects such as stomach upset, nausea and mouth ulcers have been reported in some individuals, particularly when consuming feverfew in high doses or for extended periods. Additionally, feverfew may interact with certain medications, including blood thinners and antiplatelet drugs, which could increase the risk of bleeding. Pregnant or breastfeeding individuals should avoid feverfew due to its potential to stimulate uterine contractions. As with any supplement, it’s crucial to consult with a healthcare professional before incorporating feverfew into your routine, especially if you have underlying health conditions or are taking medications, to ensure its safe and appropriate use.

Medication Interactions with Feverfew

  • Blood Thinners (Anticoagulants): Feverfew can strengthen the effects of blood thinners, heightening the risk of bleeding and bruising.
  • Antiplatelet Drugs: Taking feverfew alongside antiplatelet medications can amplify their effects, and may increase the risk of bleeding and bruising.
  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Combining feverfew supplements with NSAIDs may intensify their anti-inflammatory properties, and might raise the likelihood of gastrointestinal bleeding and ulcers.
  • Anticonvulsants (Anti-Seizure Medications): Feverfew may interact with anticonvulsants, possibly reducing their effectiveness or causing fluctuations in blood levels, which could lead to seizures or other adverse effects.
  • Methotrexate: Using feverfew alongside methotrexate, a medication commonly used for autoimmune diseases and cancer, may diminish its effectiveness.
  • Lithium: Feverfew has the potential to alter lithium levels in the blood, increase the risk of lithium toxicity or reducing its efficacy in managing mood disorders.

Supplement Interactions with Feverfew Supplements

  • Ginkgo Biloba: Ginkgo biloba may enhance the effects of feverfew supplements, and can increase the risk of bleeding due to their combined antiplatelet properties.
  • Garlic: Garlic supplements may potentiate the effects of feverfew, and may increase the risk of bleeding and bruising when used together.
  • Ginseng: Ginseng supplements can interact with feverfew, possibly leading to an increased risk of bleeding due to their combined effects on platelet function.
  • St. John’s Wort: St. John’s Wort may interact with feverfew, possibly affecting the metabolism of feverfew compounds in the body and altering their efficacy.
  • Omega-3 Fatty Acids: Omega-3 fatty acid supplements may interact with feverfew and may increase the risk of bleeding due to their combined antiplatelet effects.
  • Turmeric/Curcumin: Turmeric or curcumin supplements may interact with feverfew, enhance their anti-inflammatory effects, and increasing the risk of gastrointestinal bleeding.

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Feverfew Herb by Nature’s Way

Feverfew Herb

Feverfew has been traditionally used to support healthy blood vessel tone.*

Serving Size: 1 Veg CapsuleAmount/Serving
Feverfew (aerial parts)380 mg

Suggested Use
Take 1 capsule three times daily, preferably with food. Best results are obtained with continuous use.

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Incorporating feverfew supplements into your wellness routine can offer various health benefits. From migraine relief to anti-inflammatory support, feverfew’s natural properties have been studied for their potential in managing headaches, arthritis, and menstrual discomfort. Additionally, its antioxidant effects may contribute to overall health and well-being. As with any supplement, it’s essential to be informed about potential interactions and dosage considerations. By exploring the potential benefits of feverfew, individuals can make informed choices to support their health journey.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


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