Beating Candida: A Guide to Nutritional Supplements for Candida Control

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Along with providing information on whether these candida supplements might be right for you, this article also links to Fullscript where you can buy supplements for candida overgrowth. Order online through Fullscript’s secure healthcare formulary to get the best prices and free shipping on professional-grade supplements.

Candida naturally exists in the human body, mainly in the gut, mouth, and skin. While it’s generally harmless in small amounts, an overgrowth can lead to infections, commonly known as candidiasis, which can affect various parts of the body. Managing Candida overgrowth is important because it can cause a range of symptoms, from digestive issues to fatigue and skin irritation. Keeping Candida levels in check can help maintain overall well-being, support the immune system, and prevent more serious health problems from developing.

What Is Candida Overgrowth?

Candida Explained Candida is a type of yeast that naturally exists in the human body, particularly in the digestive system, mouth, and vagina. Usually, it coexists peacefully with other microorganisms. However, an imbalance can lead to Candida overgrowth, which may cause a range of health issues.

What Are The Symptoms And Causes of Candida?

Symptoms of Candida Overgrowth

  • Fatigue
  • Digestive problems like bloating and constipation
  • Recurring yeast infections
  • Skin issues like rashes and eczema
  • Brain fog
  • Mood swings

Causes of Candida Overgrowth

  • Antibiotic use: Kills beneficial bacteria, allowing Candida to multiply
  • High-sugar diet: Provides yeast with the fuel it needs to grow
  • Stress: Weakens the immune system, making it harder to keep Candida in check
  • Hormonal imbalances: Changes in hormone levels can disrupt the natural balance of microorganisms
  • Weakened immune system: Allows Candida to grow more easily

What Is A “Die-Off” or Herx Reaction

Die-Off or Herx Reaction Explained A “die-off” or Herxheimer reaction occurs when a large number of harmful microorganisms like Candida die at the same time, releasing toxins into the body. This can lead to a temporary worsening of symptoms as the body tries to eliminate these toxins.

Symptoms of Die-Off or Herx Reaction

  • Headaches
  • Fatigue
  • Muscle or joint pain
  • Skin rashes
  • Fever or chills
  • Nausea

Causes of Die-Off or Herx Reaction The primary cause is the rapid killing of microorganisms, often due to starting a new medication, supplement, or diet aimed at combating an infection like Candida overgrowth. The mass die-off leads to a surge in released toxins, which can overwhelm the body’s detoxification pathways.

How to Avoid Die-Off or Herx Reaction

  • Start slow: Gradually introduce antifungal supplements or medications.
  • Stay hydrated: Drinking water can help flush toxins from the body.
  • Take liver support: Consider natural liver support like milk thistle to aid detoxification.
  • Limit sugar: Reducing sugar can help mitigate the fuel source for yeast and bacteria, leading to a slower die-off.
  • Exercise moderately: Light exercise can help the lymphatic system remove toxins but avoid overexerting yourself.

What Other Food and Lifestyle Factors Are Important For Managing Candida Overgrowth?

  • Food Choices: [PMID: 30166063]
    • Low-Sugar Diet: Reducing sugar intake can starve Candida yeast cells, preventing overgrowth.
    • High-Fiber Foods: Foods rich in fiber can support the digestive system and help prevent Candida overgrowth in the gut.
    • Hydration: Drinking enough water helps flush toxins from the body, which can support overall well-being and keep Candida levels in check.
    • Limit Alcohol: Alcohol can contribute to Candida overgrowth and should be consumed in moderation, if at all.
    • Avoid Processed Foods: Processed foods can contain hidden sugars and unhealthy fats that may promote Candida overgrowth.
    • Probiotic-Rich Foods: Foods like yogurt, sauerkraut, and kimchi contain beneficial bacteria that can help balance gut flora.
  • Regular Exercise: Physical activity boosts the immune system, helping the body keep Candida in check.
  • Stress Management: Stress can weaken the immune system, making it easier for Candida to grow. Mindfulness, meditation, and relaxation techniques can help.
  • Adequate Sleep: Lack of sleep can weaken the immune system, making it important to get enough rest to help the body fight off Candida.
  • Good Hygiene: Keeping skin dry and clean can prevent the spread of yeast, especially in areas like the mouth, throat, and genital region.

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. This article aims to offer valuable insights into which nutritional supplements have undergone scientific study and shown promise in supporting specific health conditions. We break down the research, so you can work with your medical providers to make informed decisions about adding supplements to your health regimen. For personalized advice tailored to your needs, we recommend consulting with a registered dietitian in addition to your primary care provider.

Check with your physician when adding supplements. While supplements are generally safe for most people, do not add nutritional supplements without your physician’s specific approval if you are pregnant or nursing, are undergoing cancer treatment, have a history of organ transplant, liver or kidney disease, or take medications that interact with supplements.


  • Probiotics: Probiotics help manage Candida by restoring a healthy balance of gut flora. When the bacterial balance in your gut is off, it can create an environment where Candida thrives. Probiotics introduce beneficial bacteria into the gut, creating a more hostile environment for Candida overgrowth. These beneficial bacteria compete with Candida for resources, effectively helping to limit its ability to multiply uncontrollably. By restoring and maintaining a healthy gut ecosystem, probiotics can play a crucial role in keeping Candida levels in check. [PMC2919387]
  • Garlic: Garlic contains natural antifungal properties that can help control Candida overgrowth. The active compounds in garlic, such as allicin, have shown effectiveness in inhibiting the growth and spread of Candida in the body. By disrupting the cell walls of Candida yeast, garlic makes it harder for the fungus to spread and thrive. This makes garlic a useful supplement for those looking to manage Candida levels. It can be incorporated into your diet or taken as a supplement. [PMC7402177]
  • Caprylic Acid: Caprylic acid is a fatty acid found in coconut oil that has antifungal properties, making it useful for combating Candida overgrowth. It works by breaking down the cell walls of the Candida yeast, making it easier for the body to eliminate the fungus. The disrupted cell walls weaken the Candida cells, limiting their ability to spread and cause infection. This makes caprylic acid a popular supplement for those managing Candida levels. [PMID: 28922057] The amount of caprylic acid in coconut oil is estimated to be around 5 to 7% of the total fatty acid content. A tablespoon of coconut oil typically contains about 13.6 grams of total fat, so it could contain approximately 0.68 to 0.95 grams of caprylic acid.
  • Oregano Oil: Oregano oil is considered helpful in managing Candida due to its active compound, carvacrol. Carvacrol is believed to have antifungal properties that can inhibit the growth of Candida yeast. When applied, oregano oil can disrupt the integrity of the fungal cell membrane, leading to leakage of cellular contents and eventually cell death. This makes it easier for the body to eliminate the Candida overgrowth. Oregano oil may be used in various forms, such as topical application or oral supplements, to target different types of Candida infections. [PMC7203418]
  • Berberine: Berberine acts on Candida cells by disrupting their metabolic functions and cellular structure. Its antimicrobial properties inhibit Candida growth by targeting key enzymes and altering the yeast’s gene expression. These actions lead to the disruption of Candida cell walls and interfere with its ability to proliferate. [PMID: 33645065]It is noted to help with drug resistant forms of C. albicans [PMID: 36654399]
  • Undecylenic Acid: Undecylenic Acid works as an antifungal agent against Candida by disrupting the yeast’s cellular membrane. This disruption weakens the integrity of the Candida cells, making it difficult for the yeast to maintain its structure and function. By doing so, undecylenic acid helps in preventing the overgrowth of Candida, supporting a balanced intestinal and vaginal flora. The acid also targets the enzymes responsible for converting yeast cells into their more aggressive fungal form, inhibiting the yeast’s ability to spread and cause infection. Candida biofilm is also disrupted by Undecylenic Acid. [PMID: 26902505]

Other supplements commonly used for Candida include grapefruit seed extract, which has antimicrobial properties that may disrupt the membrane of yeast cells. Pau d’Arco is another supplement that contains naphthoquinones, compounds that demonstrate antifungal activity. Digestive enzymes are also used to help break down the biofilm that Candida can create as a protective barrier. Zinc helps support the immune system, which plays a role in fighting off Candida overgrowth. Finally, aloe vera has shown some promise due to its natural antiseptic properties, although more research is needed in this area. These are just a few of the supplements that are sometimes incorporated into a regimen to manage Candida overgrowth.

When you purchase linked products presented on this page, Supplement Sciences, LLC receives affiliate fees so that our dietitians can continue to create great content.

Thank you for your support!

Why Professionals Choose the Fullscript Formulary

Your health is on the line. Health professionals know that many other online and retail options set a very low bar for quality–sometimes amazingly low. The Fullscript formulary is the most secure online source for the highest quality brands securely sourced to assure freshness and purity. Here’s what makes Fullscript the best:

  • Meticulous vetting of brand quality. Health professionals trust Fullscript to continuously monitor the quality of each item on the platform. Other retailers operate with profit as their highest or only motive when choosing brands. Fullscript cares only about quality and reliability. Unlike discount stores, large online marketplaces, and other retailers you won’t find ingredients sourced from China or other questionable locations or companies.
  • Free shipping over $50 and best prices when you order through Supplement Sciences.
  • Freshness. Fullscript prioritizes freshness over bulk buying even if it means an increased risk of briefly being out of stock.
  • Top quality phone and online support. When you call, knowledgeable humans at Fullscript answer your questions.
  • How It Works:
    • Easy Sign-up & No Spam Email: Click the “View Product” button below to be taken to Fullscript’s login page where you can quickly create your secure account with just your name, email, and phone number. Then you will be taken directly to the product page.
    • Wide variety of supplement options: Once you sign in to your account, you are not limited to the products listed below. You will see similar items listed at the bottom of each product page on Fullscript.
    • Search For What You Want: Once inside Fullscript, you can search for the exact brands and products you want from their wide selection of quality brands.

Are These Candida Supplements Safe?

Probiotics, Garlic, Caprylic Acid, Oregano Oil, Berberine, and Undecylenic Acid are generally considered safe when used as directed for managing Candida. Probiotics naturally exist in the gut and help balance gut flora, while garlic has been consumed for centuries and contains natural antifungal properties. Caprylic Acid is a fatty acid found in coconut oil, and Oregano Oil is a natural extract. Berberine is an alkaloid extracted from various plants, and Undecylenic Acid is a naturally occurring fatty acid. It’s important to note that these supplements should be used under the guidance of a healthcare provider, especially if you are pregnant, nursing, or taking other medications.

Medication Interactions With Candida Supplements

  • Warfarin: Probiotics may alter the effects of warfarin by changing gut flora that contribute to its metabolism. Garlic may increase the risk of bleeding when taken with warfarin.
  • Anti-diabetic Medications (Berberine): May lower blood sugar levels, potentially causing hypoglycemia when combined with anti-diabetic medications. May interfere with the action of calcium channel blockers and other heart medications by affecting the same metabolic pathways. Can also potentially interact with hormone medications, affecting their metabolism.
  • Anti-diabetic Medications (Garlic): May also lower blood sugar levels.
  • Blood Pressure Medications (Garlic): Can potentially lower blood pressure and may interact with medications designed to do the same.
  • Antiplatelet/Anticoagulant Medications (Oregano Oil): Contains compounds that might act as blood thinners, interacting with antiplatelet or anticoagulant medications.
  • Cytochrome P450 Substrates (Berberine): May interact with drugs metabolized by CYP enzymes, potentially affecting drug levels in the body.
  • Hormonal Contraceptives (Caprylic acid or garlic): Can affect the liver’s ability to process medications, including hormonal drugs, leading to altered medication levels in the bloodstream.
  • Hormonal Contraceptives (Undecylenic Acid): Although not well-studied, there is some concern that it could potentially affect the efficacy of hormonal contraceptives.

Candida Supplement Interactions

  • Probiotics: May interact with antibiotic medications. Also, some strains could bind to iron supplements, potentially affecting iron absorption.
  • Garlic: Can enhance the effects of antifungal medications, leading to increased risk of side effects.
  • Caprylic Acid: May have a synergistic effect with antifungal medications, possibly amplifying their antifungal properties.
  • Oregano Oil: Its antifungal components might amplify the effects of antifungal medications, raising the possibility of increased side effects.
  • Undecylenic Acid: Might interact with other antifungal herbal supplements, potentially increasing their effects.

When you purchase linked products presented on this page, Supplement Sciences, LLC receives affiliate fees so that our dietitians can continue to create great content.

Thank you for your support!

Order Supplements For Candida

Why Professionals Choose the Fullscript Formulary

Your health is on the line. Health professionals know that many other online and retail options set a very low bar for quality–sometimes amazingly low. The Fullscript formulary is the most secure online source for the highest quality brands securely sourced to assure freshness and purity. Here’s what makes Fullscript the best:

  • Meticulous vetting of brand quality. Health professionals trust Fullscript to continuously monitor the quality of each item on the platform. Other retailers operate with profit as their highest or only motive when choosing brands. Fullscript cares only about quality and reliability. Unlike discount stores, large online marketplaces, and other retailers you won’t find ingredients sourced from China or other questionable locations or companies.
  • Free shipping over $50 and best prices when you order through Supplement Sciences.
  • Freshness. Fullscript prioritizes freshness over bulk buying even if it means an increased risk of briefly being out of stock.
  • Top quality phone and online support. When you call, knowledgeable humans at Fullscript answer your questions.
  • How It Works:
    • Easy Sign-up & No Spam Email: Click the “View Product” button below to be taken to Fullscript’s login page where you can quickly create your secure account with just your name, email, and phone number. Then you will be taken directly to the product page.
    • Wide variety of supplement options: Once you sign in to your account, you are not limited to the products listed below. You will see similar items listed at the bottom of each product page on Fullscript.
    • Search For What You Want: Once inside Fullscript, you can search for the exact brands and products you want from their wide selection of quality brands.

Ordering Options

As you can see, there are many good supplement options for fighting candida and each one has a unique set of health benefits beyond gut health. Even before you begin supplements, start with diet and lifestyle above to reduce your candida load so that when you begin your supplements, there will be less risk for a “die-off” reaction when supplements are added. Begin with low doses at each meal and progressively increase the dose or number of supplements you are taking to combat candida.

If you are looking for a single product to get started with treating Candida, or to keep Candida at under control after treatment, the combination product below may be a good choice for your situation.

Candidase Extra Strength by Enzymedica

Complete blend of enzymes and synergistic herbs to help promote balanced yeast levels
1 capsule 15 minutes before each meal, three times daily for 14 days. 

Amount Per 1 Capsule Serving
Potassium … 6mg
(from Potassium Gluconate)
Propietary Blend … 263mg
Garlic powder (Allium sativum)(Bulb)
Grape seed extract (Vitis vinigera)
Lysozyme (from egg)
Oregano oil (Origanum vulgare)(18% carvacrol)
Thyme oil (Thymus vulgaris)(3% thymol)
Clove oil (Syzygium aromaticum)(2.5% eugenol)
Peppermint leaf extract
Bascillius subtillis … 1 billionCFU
Hemicellulase … Hemicellulose … 20000HCU
Protease Thera-blend™ … 10000HUT
Cellulase Thera-blend™ … 500CU

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

To wrap things up, Probiotics, Garlic, Caprylic Acid, Oregano Oil, Berberine, and Undecylenic Acid offer a range of health benefits that can be particularly useful in managing Candida. From restoring gut flora with probiotics to breaking down Candida cell walls with caprylic acid, these supplements can be a valuable part of your Candida management strategy. However, like all supplements, it’s crucial to use them wisely and be aware of any interactions they may have with other medications or supplements you’re taking. For personalized advice tailored to your needs, a consultation with a Registered Dietitian can provide invaluable insights. So take the next step in your health journey by seeking expert guidance.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


About the Author

Stephanie Figon, MS, RDN, LD

Creator of Supplement Sciences and NutriScape.NET. As a dietitian since 1992, Steph has had experiences in consulting, 15 years in clinical, and has operated a private practice nutrition counseling office for since 2011. Log in to comment and save this article on your board or send your comments to reviews@supplement-sciences.com

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