Apple Cider Vinegar

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Along with providing information on whether cider vinegar or cider vinegar supplements might be right for you, this article also links to Fullscript where you can buy cider vinegar supplements online through Fullscript’s secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

We’ll explore the health benefits of apple cider vinegar supplements. Derived from fermented apple juice, these supplements have gained popularity for their potential to support health. We’ll examine the scientific evidence behind their use and their impact on weight management, blood sugar control, heart health, digestive health, and more. Let’s uncover the facts behind this ancient remedy and its modern applications.

What Is Apple Cider Vinegar?

Apple cider vinegar is a type of vinegar produced from fermented apple juice. The fermentation process involves yeast converting sugars into alcohol, followed by bacteria converting the alcohol into acetic acid, the main compound in vinegar. Apple cider vinegar has been used for culinary and medicinal purposes for centuries due to its high acetic acid content and other bioactive compounds like polyphenols.

Apple cider vinegar is commonly available as a liquid or in capsule form, often consumed as a health supplement. Some health benefits associated with apple cider vinegar include weight management, blood sugar control, heart health, digestive health, and antimicrobial properties. Research suggests Apple cider vinegar may aid in weight loss by increasing feelings of fullness and may reduce calorie intake. It may also improve insulin sensitivity and lower blood sugar levels, reduce cholesterol and blood pressure, alleviate indigestion symptoms, and combat harmful bacteria and pathogens.

What Are the Benefits of Apple Cider Vinegar?

  • Weight management: Apple cider vinegar supplements may aid in weight loss by increasing feelings of fullness and boosting metabolism, thus helping to reduce calorie intake and burn more calories for energy. Additionally, combining vinegar with probiotics like B. coagulans could reduce food intake, slow weight gain, improve blood sugar levels, and lower cholesterol levels, suggesting potential benefits for fighting obesity and improving metabolic health. PMC7551919
  • Blood sugar control: Apple cider vinegar has shown promising effects on blood sugar control, especially after meals, by improving insulin sensitivity and glucose utilization, leading to reduced spikes in blood sugar levels. Research suggests that regular consumption of apple cider vinegar may benefit metabolic health, as it has been associated with decreased total cholesterol and fasting blood sugar levels in adults. Specifically, in individuals with type 2 diabetes, drinking 30 ml of apple cider vinegar daily for eight weeks resulted in significant reductions in fasting blood sugar and hemoglobin A1C levels, indicating its potential role in managing blood sugar levels. PMC8243436, PMC10679383
  • Heart health: Research indicates that apple cider vinegar may positively influence heart health by lowering cholesterol levels and blood pressure. High cholesterol and blood pressure are major risk factors for cardiovascular diseases like heart attacks and strokes. Incorporating apple cider vinegar into the diet could help manage these risk factors and promote a healthier heart. PMID: 36152934
  • Antimicrobial properties: Apple cider vinegar’s primary component, acetic acid, has antimicrobial properties that can combat harmful bacteria and pathogens. Research suggests that diluted apple cider vinegar may be effective against various microbes, including bacteria, fungi, and antibiotic-resistant strains like MRSA and rE.coli. This makes apple cider vinegar a natural remedy for minor infections and skin conditions, such as acne or fungal infections. PMC5788933, PMC7817673
  • Potential antioxidant properties: Apple cider vinegar contains polyphenols, which are antioxidants that help neutralize harmful free radicals in the body. These antioxidants may help protect cells from oxidative damage, which is associated with aging and various chronic diseases. The studies showed that ACV improved antioxidant enzyme activity, reduced oxidative damage, and protected the liver and kidneys from harm caused by diabetes. Overall, ACV appears to have benefits for managing diabetes and preventing complications. PMID: 31140380
  • Improved skin health: Some people use Apple cider vinegar topically as a skin toner or to treat conditions like acne, as its antimicrobial properties may reduce acne-causing bacteria and balance the skin’s pH levels. Vinegar also possesses antimicrobial and antioxidant properties that provide utility in wound care, bacterial and fungal infections, itching, and head lice removal, which could further improve overall skin health. PMID: 34350993

Vinegar and Blood Sugar Control

Studies have shown that vinegar can help lower after-meal blood glucose levels. The effect of vinegar on blood sugar levels is thought to be a result of acetic acid, which is present in all types of vinegar, including both standard white vinegar and apple cider vinegar. Acetic acid is believed to slow down the rate of glucose absorption into the bloodstream and can improve insulin sensitivity.

The majority of research focusing on vinegar’s effects on blood glucose levels does not always specify the type of vinegar used, but apple cider vinegar is often highlighted in studies and popular health discussions due to its other health-promoting properties and the belief that it may provide additional benefits beyond its acetic acid content.

However, the primary mechanism through which vinegar affects blood glucose levels—slowing gastric emptying and modifying the action of enzymes involved in carbohydrate digestion—is a function of its acetic acid component. This suggests that standard white vinegar, which also contains acetic acid, should theoretically have a similar effect on postprandial glucose levels as apple cider vinegar.

How Does Vinegar Reduce Blood Sugar?

Vinegar, primarily through its active component acetic acid, improves insulin sensitivity by affecting the body’s response to sugars and insulin in several ways. The exact mechanisms are complex and not fully understood, but research suggests several key pathways through which vinegar may exert its effects:

  • Slows Stomach Emptying: Vinegar can slow down the rate at which food leaves the stomach, leading to a more gradual absorption of glucose into the bloodstream. This slower absorption rate can prevent rapid spikes in blood glucose and insulin levels, which in turn helps improve insulin sensitivity over time. A study comparing artisanal and industrial apple vinegar found that artisanal vinegar had higher levels of healthy compounds like polyphenols and flavonoids. These compounds may help slow stomach emptying and improve digestion, making artisanal apple vinegar possibly more beneficial for health. PMC8780035
  • Blocks Enzymes: Acetic acid has been shown to inhibit enzymes that digest carbohydrates, such as amylase, sucrase, maltase, and lactase. This slows down the breakdown of complex carbohydrates into sugars that are absorbed into the bloodstream, reducing the post-meal blood glucose spike. A study compared artisanal and industrial apple vinegar to see which had better health benefits. They measured things like pH, acidity, and the amount of certain compounds like polyphenols and flavonoids. The artisanal vinegar had more of these healthy compounds and better effects on enzymes related to blood sugar control. PMC8780035
  • Improves Muscle Uptake: Vinegar may enhance glucose uptake by skeletal muscles, which are significant consumers of glucose in the body. By improving the muscles’ ability to utilize glucose, vinegar helps lower blood glucose levels and reduces the burden on insulin to facilitate glucose absorption. A study about how acetic acid, found in vinegar, affects glycogen replenishment after exercise. Studies show that adding acetic acid to glucose helped muscles replenish glycogen faster, suggesting that vinegar could aid in muscle recovery after exercise. PMC4438142
  • Affects Insulin Signaling: Some studies suggest that vinegar can affect insulin signaling pathways in the liver and muscle tissue, enhancing the effectiveness of insulin in these tissues. Improved insulin signaling helps in the more efficient uptake of glucose from the bloodstream, improving insulin sensitivity. A study investigated the impact of acetic acid, found in vinegar, on glycogen replenishment in swimming exercises. Results showed that combining glucose with acetic acid accelerated glycogen repletion in muscles, aiding in post-exercise recovery and influencing insulin signaling. PMC4438142
  • Alters Glycogen Repletion: Vinegar consumption has been associated with alterations in liver glycogen levels. Acetic acid might influence the way the liver stores glucose as glycogen and how it releases glucose into the bloodstream, which can affect overall blood sugar control. A study on vinegar’s main component, acetic acid, affects glycogen replenishment after exercise. The study found that acetic acid helped replenish glycogen in muscles faster than glucose alone, suggesting vinegar might aid in restoring energy levels after exercise. PMID: 11914987

Is Apple Cider Vinegar Safe?

Apple cider vinegar is safe for most people when consumed in moderate amounts. It has a long history of culinary and medicinal use with few reported adverse effects. Diluting apple cider vinegar with water or other liquids can help prevent irritation to the throat and stomach lining, as its high acidity may cause discomfort when consumed undiluted. Additionally, excessive consumption of apple cider vinegar may lead to tooth enamel erosion and digestive issues. Overall, when used appropriately and in moderation, apple cider vinegar is a safe and beneficial addition to a healthy lifestyle.

Medication Interactions with Apple Cider Vinegar

  • Diabetes medications (e.g., insulin, metformin): Apple cider vinegar may lower blood sugar levels, so when taken in conjunction with diabetes medications, it can enhance their effects, leading to hypoglycemia (low blood sugar). Monitoring blood sugar levels closely and adjusting medication dosage as necessary is recommended.
  • Digoxin (Lanoxin): ACV may decrease potassium levels in the body, which can enhance the effects of digoxin, a medication used to treat heart conditions. This interaction could lead to an irregular heartbeat or other cardiac complications. Regular monitoring of potassium levels and cardiac function is advised.
  • Certain diuretics (e.g., furosemide, hydrochlorothiazide): Apple cider vinegar may also lower potassium levels, which can increase the effects of diuretics, leading to electrolyte imbalances such as hypokalemia (low potassium levels). Close monitoring of potassium levels and adjustments to medication dosage may be necessary.
  • Certain medications for osteoporosis (e.g., alendronate, risedronate): Apple cider vinegar may reduce the body’s ability to absorb calcium, which is essential for bone health. Taking Apple cider vinegar with medications for osteoporosis may decrease the effectiveness of these drugs. It is advisable to separate the intake of Apple cider vinegar and osteoporosis medications by at least two hours to minimize potential interactions.

Supplement Interactions with Apple Cider Vinegar

  • Potassium supplements: Apple cider vinegar (ACV) may lower potassium levels in the body, so combining it with potassium supplements could lead to further decreases in potassium levels, resulting in hypokalemia (low potassium levels). Monitoring potassium levels and adjusting supplement dosage may be necessary to avoid complications.
  • Iron supplements: ACV may interfere with the absorption of iron from supplements or food sources. Taking ACV alongside iron supplements may reduce the body’s ability to absorb iron effectively, possibly leading to iron deficiency anemia over time. To mitigate this interaction, it’s advisable to take iron supplements at a different time than ACV.
  • Calcium supplements: Similar to iron, ACV may also hinder the absorption of calcium from supplements or dietary sources. Combining ACV with calcium supplements could decrease calcium absorption, could impact bone health and increasing the risk of osteoporosis. Separating the intake of ACV and calcium supplements by at least two hours may help minimize this interaction.
  • Medications or supplements containing chromium: ACV may contain trace amounts of chromium, and combining it with chromium supplements or medications containing chromium could lead to excessive chromium intake. High levels of chromium may have adverse effects on health, including gastrointestinal issues and kidney damage. Careful monitoring and adjustment of supplement or medication dosage may be necessary when combining ACV with chromium-containing products.
  • B-vitamin supplements: ACV’s acidic nature may interfere with the absorption of certain B vitamins, particularly B12. Taking ACV alongside B-vitamin supplements could reduce the body’s ability to absorb these vitamins effectively, possibly leading to deficiencies over time. Separating the intake of ACV and B-vitamin supplements by at least two hours may help mitigate this interaction.
  • Fiber laxatives (e.g., psyllium, methylcellulose): Apple cider vinegar’s acidic nature may interfere with the effectiveness of fiber laxatives, especially those that rely on a more alkaline environment to work. It’s recommended to take ACV and laxatives at different times to avoid potential interactions.

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Apple Cider Vinegar 450mg By NOW Foods

Apple Cider Vinegar is derived from the natural fermentation of sweet apple cider. Vinegar has been used worldwide for more than 2000 years for various culinary purposes. More recently, it has been recognized for its acidic properties. Natural color variation may occur in this product. Suggested Use: Take 1-2 capsules up to 3 times daily with food.

Amount Per 2 Veg Capsule Serving
Apple Cider Vinegar Powder
 … 900mg

Other Ingredients: Maltodextrin, Hypromellose (cellulose capsule), Stearic Acid (vegetable source) and Silicon Dioxide.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Organic Apple Cider Vinegar by Omega Nutrition

Certified-organic, kosher, unfiltered, and non-pasteurized.

Omega’s Certified-Organic Apple Cider Vinegar is made the “old fashioned” way, by allowing the natural fermentation process to occur to full-strength (5% acidity), without chemicals, additives, preservatives or water.

Natural sediment is the true sign of raw, unfiltered vinegar, and naturally contains pectin, trace minerals, beneficial bacteria and enzymes.

Traditionally, Apple Cider Vinegar has long been regarded as a versatile folk remedy due to its mineral content. Its crisp, zesty flavor makes salad dressings come alive.• Made from certified organic apples, and prepared and packaged in a certified organic facility.

Benefits:• Naturally contains pectin, trace minerals, beneficial bacteria and enzymes making it one of the best Apple Cider Vinegars around
• Rich in phosphorus, magnesium and manganese and is also a good source of other minerals including zinc, iron and copper

Great for salad dressing, pickling, wellness shot. Calories 0

Ingredients: Organic unfiltered apple cider vinegar.

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Apple cider vinegar supplements offer various health benefits, including aiding in weight management, supporting blood sugar control, promoting heart health, improving digestive health, and providing antimicrobial properties. These benefits are attributed to ACV’s high acetic acid content and other bioactive compounds. However, it’s essential to use ACV supplements responsibly and in accordance with recommended guidelines to maximize their potential benefits. Incorporating ACV supplements into a balanced diet and healthy lifestyle may contribute to overall health and support various aspects of health.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


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