Anticonvulsants: Critical Drug-Nutrient Interactions

Anticonvulsant include medications like Dilantin®, Lyrica®, Mysoline®, Tegertol®, Trileptal®, or others.

Folic acid, Ginko Biloba, Niacin (B3), and St. John’s wort may interfere with the effectiveness of antiepileptic drugs. DO NOT TAKE GINKO BILOBA, ST. JOHN’S WORT, OR HIGH DOSE FOLIC ACID OR NIACIN SUPPLEMENTS WITHOUT YOUR PHYSICIAN’S APPROVAL.

Vitamin D: Dilantin, Phenobarbital, and Tegretol can increase the breakdown of vitamin D, leading to a decrease in calcium absorption. People taking these medications for 6 months or more should consider calcium and vitamin D supplements. [PMID: 17445763] Vitamin D dosages should be adjusted based on your blood level with many clinicians recommending an optimal Vitamin D level of 50-80 ng/ml. Vitamin D Labs (affiliate link) can be ordered in the NutriScape Lab Shop.

Vitamin B12: Dilantin, Phenobarbital, and Mysoline have been reported to reduce vitamin B12 absorption as well as vitamin B12 levels in the brain in some individuals. B12-related anemia and neuropsychiatric side effects have been associated with these drugs. For this reason, a B12 supplement is suggested. [PMID: 21246600]

Vitamin B12 and Folate Labs: A Vitamin B12 lab test measures the levels of folate and vitamin B12 in your body. Folate and vitamin B12 are important nutrients that help your body make red blood cells and keep your nervous system healthy. Low levels of these nutrients can lead to anemia, fatigue, and other health problems. The Vitamin B12 & Folate test from Access Medical Labs (affiliate link) is available through the NutriScape Lab Shop.

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