Luteolin: Fights Brain Fog Caused By Inflammation And More

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Along with providing information on whether Luteolin supplements might be right for you, this article also links to Fullscript where you can buy supplements online through Fullscript’s secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

Whether you’re seeking to bolster your immune system, combat oxidative stress, or support overall wellness, Luteolin can be a stellar addition to your health regime.

In this article, we delve into the myriad benefits of Luteolin, exploring how this flavonoid—a type of antioxidant—can impact your health in a multitude of beneficial ways. From its anti-inflammatory properties to its role in supporting heart health and cognitive function, Luteolin truly is a plant compound worth considering.

With the rise of e-commerce and health platforms, it’s never been easier to access these beneficial supplements. For those seeking to incorporate this potent flavonoid into their health and wellness routine, you can easily buy Luteolin online.

Join us as we uncover the multifaceted benefits of Luteolin, and discover how this plant power-house can help you on your path to optimal health.

What Is Luteolin?

Luteolin is a natural substance found in many plants, fruits, and vegetables. It is a type of flavonoid, which is a group of compounds that give color to plants and have health benefits. Luteolin has a yellow color and is found in foods like celery, parsley, and chamomile tea.

What are the Health Benefits of Luteolin?

  • Brain health: Research shows that luteolin might help to protect brain cells from damage and could be useful in preventing or treating neurodegenerative diseases like Alzheimer’s disease. Brain “fog” may be due to inflammatory molecules, including adipocytokines and histamine released from mast cells further stimulating microglia activation, and causing brain inflammation. [PMC4490655]
  • Antioxidant properties: Luteolin can help protect our body from harmful molecules called free radicals, which can damage our cells and lead to health problems.
  • Anti-inflammatory effects: Luteolin may help to reduce inflammation, which is our body’s response to injury or infection.
  • Cancer prevention: Some studies suggest that luteolin might help to prevent or slow down the growth of certain types of cancer cells. [PMC10057337]
  • Heart health: Luteolin may help to improve heart health by reducing the risk of heart disease and lowering blood pressure. [PMC5635727, PMC10039598]
  • Allergy relief: Luteolin has been shown to help reduce symptoms of allergies by blocking the release of histamine, a compound that causes allergy symptoms. [PMID: 18937165]

Food Sources of Luteolin

Here’s a simple table showing some food sources of luteolin and the approximate amount of luteolin in each food:

Food SourceAmount of Luteolin (mg/3 ounces)
Celery54
Parsley48
Green Bell Peppers12
Broccoli10
Carrots6

Are Luteolin Supplements Safe?

Avoid Luteolin at Conception and in Pregnancy A study in an animal model showed that luteolin negatively affects early differentiation of embryonic stem cells. At later stages of differentiation, luteolin specifically inhibits nerve cell differentiation. [PMC6418693] With that said, Luteolin is safe in most circumstances for most people, but may interact with some medications.

Medication Interactions

Luteolin may interact with certain medications. Here’s a list of some medications that might have interactions with luteolin:

  • Blood-thinning medications: Luteolin may increase the risk of bleeding when taken with blood-thinning medications like warfarin, aspirin, or clopidogrel. This interaction can be serious, as it may lead to increased bleeding or bruising.
  • Blood pressure medications: Luteolin may lower blood pressure, so taking it with blood pressure medications like lisinopril, amlodipine, or losartan could cause blood pressure to drop too low. This interaction can be moderate, as it may lead to dizziness, fainting, or other symptoms.
  • Immunosuppressant medications: Luteolin has anti-inflammatory effects and might affect the immune system. Taking it with immunosuppressant medications like cyclosporine, tacrolimus, or sirolimus could change the effectiveness of these drugs. This interaction can be moderate, as it may affect the immune system’s response.
  • Chemotherapy drugs: Luteolin may interfere with the way some chemotherapy drugs work, like doxorubicin or paclitaxel. This interaction can be moderate to severe, as it may impact the effectiveness of the cancer treatment.
  • Medications broken down by CYP1A2: Luteolin might slow down the liver’s ability to process certain medications that are broken down by the enzyme CYP1A2. Examples of these medications include theophylline, clozapine, and tizanidine. This interaction can be moderate, as it may lead to increased side effects or reduced effectiveness of these medications.

Supplements Interactions

Luteolin may also theoretically interact with certain nutritional supplements. Here’s a list of some supplements that might have additive or synergistic interactions with luteolin:

  • Vitamin C: Vitamin C is an antioxidant, like luteolin. Taking them together might increase their antioxidant effects, which could be both beneficial or harmful depending on individual needs. It’s important to talk to a healthcare professional to determine the right balance for your needs.
  • Green Tea Extract: Green tea extract contains compounds called catechins, which may have similar effects as luteolin. Taking these supplements together might increase the risk of side effects or change the effectiveness of each supplement.
  • Quercetin: Quercetin is another flavonoid, like luteolin, with antioxidant and anti-inflammatory properties. Taking luteolin and quercetin together might enhance their effects, which could be beneficial or lead to potential side effects. It’s best to consult with a healthcare professional to determine the appropriate combination for you.
  • Gingko Biloba: Gingko biloba is a popular herbal supplement known for its potential effects on memory and cognitive function. It also has antioxidant and anti-inflammatory properties, similar to luteolin. Taking these supplements together might cause additive effects, increasing the risk of side effects or altering their effectiveness.
  • Turmeric/Curcumin: Turmeric contains a compound called curcumin, which has anti-inflammatory and antioxidant properties. Taking luteolin with turmeric or curcumin supplements might increase their combined effects, potentially leading to enhanced benefits or increased risk of side effects.

Order A Luteolin Combination Product

Why Professionals Choose the Fullscript Formulary

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NeuroFlam™ by Apex Energetics, Inc 92550

NeuroFlam™ is a phenol-flavonoid complex designed to specifically target brain health as it relates to microglial activity (in the brain-immune system) and the associated oxidative stress.* The brain-immune system plays a key role in maintaining the cellular environment in the central nervous system.* This formula also incorporates ingredients that may be involved in antioxidant processes.* Key ingredients include catechins, curcuminoids, baicalin, and apigenin. Also available in a immune-neutral product NeuroFlam™-NT (K77). Take 1-3 capsules once a day, or as directed by your healthcare professional. Do Not Take During Pregnancy.

Amount Per 1 Capsule Serving

Catechins … 100mg (from Green Tea Extract [Camellia sinensis]) (leaf)
Curcuminoids … 100mg (from Turmeric Extract [Curcuma longa]) (root)
Rutin … 75mg (from Sophora japonica) (bud)
Baicalin … 60mg (from Baikal Skullcap Extract [Scutellaria baicalensis]) (root)
Resveratrol … 50mg (from Japanese Knotweed Extract [Polygonum cuspidatum]) (root)
Apigenin … 30mg (from Chamomile Extract [Matricaria recutita]) (flower)
Luteolin … 20mg (from Chrysanthemum Extract [Dendranthema morifolium]) (leaf)

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Luteolin is a naturally occurring flavonoid found in many plants and foods. It stands out for its impressive range of health benefits. Luteolin is known for its anti-inflammatory and antioxidant properties. Additionally, it shows promise in improving brain health. This compound may also reduce the risk of chronic diseases. Thus, luteolin is not just a part of a healthy diet; it’s a potent force in enhancing overall wellness. Incorporating luteolin-rich foods into your diet, such as celery, parsley, and thyme, can be a simple yet effective way to harness these benefits. As with any dietary supplement, it’s always best to consult with a healthcare provider for personalized advice.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


About the Author

Supplement Sciences

Staff Authors at Nutriscape have been working on this article and it is still a work in progress. Please feel free to login and comment on what you see so far.

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