Krill Oil

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This article explores the natural properties of krill oil supplements and their health benefits. Krill oil is abundant in omega-3 fatty acids and antioxidants. From supporting cardiovascular health and cognitive function to aiding joint mobility and skin health, krill oil presents a range of potential advantages for overall health. Join us as we discover the scientific evidence behind krill oil and its role in promoting health.

What Is Krill Oil?

Krill oil, extracted from the depths of the icy ocean where these tiny crustaceans thrive, serves as a rich reservoir of vital nutrients essential for human health. Within its vibrant crimson hue lies a bounty of omega-3 fatty acids, notably eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), renowned for their multifaceted benefits. These fatty acids play pivotal roles in maintaining cardiovascular health by fortifying blood vessels, regulating cholesterol levels, and supporting cognitive function, including memory, concentration, and mental acuity. Moreover, krill oil is imbued with astaxanthin, a potent antioxidant that combats oxidative stress and inflammation, safeguarding cellular health and promoting longevity.

Krill oil’s distinct phospholipid structure sets it apart from conventional fish oil supplements, facilitating superior absorption and utilization by the body. This unique feature ensures maximum bioavailability of its nutritional components, minimizing the risk of adverse effects associated with higher doses of fish oil. Furthermore, the enhanced absorption of krill oil translates into greater efficiency, requiring smaller doses to achieve desired health outcomes.

Beyond its fundamental role in cardiovascular and cognitive health, krill oil shows promise in alleviating joint discomfort and promoting overall joint mobility. By mitigating inflammation and enhancing joint lubrication, krill oil offers a natural solution for persons grappling with arthritis or other inflammatory joint conditions. Additionally, emerging research suggests that krill oil’s antioxidant properties may extend to other areas of health, such as skin health and immune function, further underscoring its potential as a comprehensive wellness supplement.

In essence, krill oil emerges as a holistic powerhouse, offering various of health benefits that extend far beyond its omega-3 content. Its unique combination of omega-3 fatty acids and astaxanthin, coupled with its superior absorption profile, positions it as a valuable ally in the pursuit of optimal health and wellness. Whether fortifying cardiovascular resilience, supporting cognitive health, or alleviating joint discomfort, krill oil stands poised to deliver a comprehensive array of health-promoting nutrients, ensuring persons can thrive and flourish in every facet of life.

What Are the Benefits of Krill Oil?

  • Supports heart health: Krill oil, containing omega-3 fatty acids EPA and DHA, supports heart health by lowering triglycerides and promoting healthy cholesterol levels. A study found that krill oil supplementation improved blood lipids, antioxidants, and inflammation markers, indicating benefits for heart health without adverse effects on other heart-related factors. PMC4678523
  • Enhances brain function: The omega-3 fatty acids found in krill oil are crucial for maintaining optimal brain function, including memory, cognition, and mood regulation. Research suggests that taking krill oil for 12 weeks improves cognitive function in elderly individuals, particularly memory and calculation abilities, making it a promising supplement for brain health in older adults. PMC9641984, PMC3789637
  • Reduces inflammation: Krill oil contains astaxanthin, a potent antioxidant with anti-inflammatory effects. In a study, adults with knee osteoarthritis who took krill oil experienced reduced knee pain, and stiffness, and improved physical function, suggesting it is a safe and effective option for managing arthritis symptoms. PMC9437987, PMC9630865
  • Supports joint health: The combination of omega-3 fatty acids and astaxanthin in krill oil can help reduce joint pain and stiffness, promoting overall joint health and mobility. In a study, adults with mild knee pain who took krill oil experienced significant improvements in knee pain during activities like sleeping and standing compared to those taking a placebo, indicating its ability to alleviate joint discomfort. PMC5049853
  • Promotes skin health: The antioxidants in krill oil, particularly astaxanthin, help protect the skin from damage caused by free radicals, promoting a youthful appearance and overall skin health. Studies suggest that krill oil supplementation may also reduce wrinkles, moisturize the skin, and prevent UVB-induced damage, supporting its ability to enhance skin health and appearance. PMC10533088
  • Supports eye health: Omega-3 fatty acids are essential for maintaining eye health and may help reduce the risk of age-related macular degeneration and other vision-related conditions. Recent research suggests that a specific type of omega-3 called LPC-DHA, found in supplements like krill oil, could be particularly effective in increasing DHA levels in the eyes, offering additional benefits for eye health. PMC7601701
  • Reduced menstrual discomfort in PMS: Krill oil supplements may help alleviate symptoms of premenstrual syndrome (PMS) and menstrual cramps in some women. In a study comparing Krill Oil with omega-3 fish oil, krill oil was found to be more effective in reducing PMS symptoms and relieving period pain over three months. [PMID: 12777162]
  • Improved liver health: Some research suggests that krill oil may help support liver health by reducing inflammation and oxidative stress in the liver. In a study where krill oil was supplemented alongside a high-fat diet for 28 weeks, it was found to reduce inflammation in the liver and improve metabolism, offering benefits for managing obesity-related liver issues. PMC8401900
  • Enhanced exercise performance: Krill oil supplements may support exercise performance and recovery by reducing exercise-induced inflammation and muscle soreness. In a study of athletes, those taking krill oil showed increased omega-3 levels in their blood and improved choline recovery after intense workouts, suggesting its benefits for athletic performance and recovery. PMC8708578

Is Krill Oil Safe?

Krill oil is safe for most people when taken at recommended dosages. It is extracted from krill, a type of small crustacean, and is processed to reduce contaminants, ensuring a high level of purity. Unlike some fish oil supplements, krill oil is less likely to be contaminated with heavy metals due to krill’s position at the lower end of the food chain. Moreover, krill oil’s phospholipid-bound form of omega-3 fatty acids enhances its absorption, reducing the risk of unpleasant digestive side effects often associated with fish oils.

Medication Interactions with Krill Oil

  • Anticoagulant medications (e.g., Warfarin, Coumadin): Krill oil may increase the risk of bleeding when taken with anticoagulant medications due to its blood-thinning properties. It is essential to monitor blood clotting parameters closely and adjust medication doses as necessary.
  • Antiplatelet medications (e.g., Aspirin, Clopidogrel): Krill oil may enhance the effects of antiplatelet medications, leading to an increased risk of bleeding. Close monitoring of bleeding parameters and adjustment of medication doses may be necessary when combining krill oil with antiplatelet drugs.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., Ibuprofen, Naproxen): Krill oil may increase the anti-inflammatory effects of NSAIDs, possibly increasing the risk of gastrointestinal bleeding and other adverse effects associated with NSAID use. Caution and monitoring for signs of bleeding or gastrointestinal irritation are advised when taking krill oil concurrently with NSAIDs.
  • Blood pressure medications (e.g., ACE inhibitors, Beta-blockers): Krill oil may have mild blood pressure-lowering effects. When taken with blood pressure medications, krill oil may enhance the hypotensive effects, leading to a further reduction in blood pressure. Regular monitoring of blood pressure levels is recommended, and medication doses may need to be adjusted accordingly.
  • Diabetes medications (e.g., Insulin, Metformin): Krill oil may slightly lower blood sugar levels. When combined with diabetes medications, krill oil may enhance the hypoglycemic effects, necessitating close monitoring of blood glucose levels. Adjustment of diabetes medication doses may be necessary under the supervision of a healthcare provider.

Supplement Interactions with Krill Oil

  • Fish oil: Combining krill oil with fish oil may result in an increased intake of omega-3 fatty acids, leading to enhanced health benefits associated with omega-3 supplementation. However, it is essential to monitor total omega-3 intake to avoid excessive consumption and increase side effects such as gastrointestinal discomfort or bleeding.
  • Vitamin E: Vitamin E is an antioxidant that may complement the antioxidant properties of astaxanthin found in krill oil. Together, they may provide synergistic benefits in combating oxidative stress and inflammation. However, caution is advised when combining high doses of vitamin E with krill oil, as excessive antioxidant intake may have adverse effects.
  • Coenzyme Q10 (CoQ10): CoQ10 is a compound involved in cellular energy production and antioxidant defense. Combining CoQ10 with krill oil may offer complementary benefits in supporting cardiovascular health and cellular function. However, persons should follow appropriate dosages and monitor for any interactions.
  • Glucosamine/chondroitin: Glucosamine and chondroitin are commonly used to support joint health and alleviate symptoms of osteoarthritis. When taken with krill oil, these may provide synergistic effects in promoting joint lubrication and reducing inflammation. However, persons should be cautious of potential interactions before combining these.
  • Vitamin D: Vitamin D plays a crucial role in bone health, immune function, and overall health. When taken with krill oil, vitamin D may complement the benefits of omega-3 fatty acids and astaxanthin in supporting immune function and inflammatory response.

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Neptune Krill Oil 500mg by Protocol for Life Balance

Neptune Krill Oil (NKO®) is known for its unique fatty acid (FA) profile, which includes EPA and DHA, plus phospholipids. In addition, NKO® naturally has Astaxanthin, a powerful free radical scavenger and immune-supporting carotenoid.* Clinical studies have shown that NKO® can help to support joint comfort, healthy blood lipid levels already within normal range, and may help to maintain healthy feminine balance.* The Phospholipid-bound forms of EPA and DHA from Krill Oil have also demonstrated exceptionally high bioavailability.* Neptune Krill Oil is manufactured under strict quality control standards. It is tested to be free of potentially harmful levels of contaminants (i.e. mercury, heavy metals, PCB’s, dioxins, and other contaminants).

NKO® is a registered trademark of Neptune Technologies & Bioressources Inc. Quebec, Canada. US Patent No.: 8, 278, 351.

Take 2 softgels twice daily, or as directed by your healthcare practitioner.

Amount Per 2 Softgel Serving
Neptune Krill Oil … 1g (1, 000mg) (NKO®)
Omega-3 Fatty Acids … 230mg
Eicosapentaenoic Acid … 120mg (EPA)
Docosahexaenoic Acid … 70mg (DHA)
Phospholipids … 390mg
Esterified Astaxanthin … 750mcg

Other Ingredients: Softgel Capsule (bovine gelatin, glycerin, water) and Glycerin. Contains shellfish (krill).

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

What To Eat

To Sum It Up

Krill oil supplements can offer a range of health benefits. From supporting heart health and promoting brain function to enhancing joint mobility and reducing inflammation, krill oil provides a natural source of essential omega-3 fatty acids and potent antioxidants. Its superior absorption and utilization by the body make it a valuable addition to your wellness regimen. Whether you’re looking to maintain cardiovascular resilience, support cognitive health, or alleviate joint discomfort, krill oil stands out as a holistic solution for overall health.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


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