Feverfew Facts: Migraine Relief and More

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Along with providing information on whether Feverfew supplements might be right for you, this article also links to Fullscript where you can buy supplements online through Fullscript’s secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

Feverfew is a herb that people have praised for its medicinal properties for centuries. Originating in the Balkan Peninsula, it’s now found all around the globe. While scientific studies are still exploring all its features, early research points to a range of benefits, from migraine relief to anti-inflammatory effects. This article delves into what makes feverfew worth considering in your wellness routine.

What Is Feverfew?

Feverfew is a flowering plant belonging to the daisy family. It’s native to the Balkan Peninsula but has spread to other parts of the world, including North America and Europe. The plant has small, white flowers with a yellow center, resembling a daisy. People often use its leaves, either fresh or dried, to make teas or extracts. Feverfew has been a part of traditional medicine for many years, particularly for conditions like migraines, headaches, and arthritis. Scientific research is ongoing to fully understand its properties and benefits. Whether you consume it as a tea or take it in supplement form, feverfew offers an array of uses that make it a noteworthy addition to your health regimen.

What Are the Benefits of Feverfew?

  • Migraine Relief: Some studies suggest that feverfew can reduce the frequency and severity of migraines. A Cochrane review reported it reduced migraine frequency by 0.6 per month. [PMC7133498]
  • Anti-Inflammatory Properties: Compounds in feverfew, like parthenolide, have shown anti-inflammatory effects.
  • Eases Menstrual Cramps: Feverfew may help alleviate discomfort related to menstrual cramps. [PMC3210009]
  • Reduces Stress and Anxiety: Some users report that feverfew helps in calming nerves and reducing stress.
  • Helps with Arthritis: Traditional uses of feverfew include reducing symptoms of arthritis, although more research is needed.
  • Enhances Digestive Health: Feverfew has been used traditionally to relieve indigestion and improve overall digestive well-being.

Flowers and leaves and parthenolide showed significant analgesic, anti-inflammatory and antipyretic activities, which confirmed the folk use of feverfew herb for treatment of migraine headache, fever, common cold, and arthritis, and these effects are attributed to leaves and/or flowers mainly due to the presence of sesquiterpene lactones and flavonoids.

Feverfew (Tanacetum parthenium L.): A systematic review [PMC3210009]

Is Feverfew Safe?

When it comes to safety, feverfew has a good track record. Many people consume it with minimal side effects, and it has been a part of traditional medicine for centuries. However, like any supplement or herb, it’s essential to exercise caution. If you’re pregnant, nursing, or taking other medications, consult your healthcare provider before adding feverfew to your regimen. High doses (2400 mg/d) over a long period have been reported to cause issues with bleeding. [PMC8383641] Also, be aware that feverfew can cause allergic reactions in people who are sensitive to plants from the Asteraceae family, like chrysanthemums, marigolds, or daisies. Start with a lower dose to see how your body reacts, and increase gradually as needed.

Medication Interactions with Feverfew

  • Blood Thinners: Such as warfarin or aspirin. Feverfew may increase the risk of bleeding.
  • Antidepressants: Particularly SSRIs like fluoxetine or sertraline, due to potential for increased serotonin levels.
  • Blood Pressure Medications: Feverfew may interact with medications designed to regulate blood pressure.
  • NSAIDs: Like ibuprofen or naproxen, because feverfew also has anti-inflammatory properties.
  • Antiplatelet Drugs: Such as clopidogrel, as feverfew may affect platelet aggregation.
  • Certain Antacids: Like omeprazole, as they may interfere with how feverfew is absorbed in your body.

Supplement Interactions with Feverfew

  • Ginkgo Biloba: Both supplements have blood-thinning properties, which could increase the risk of bleeding.
  • St. John’s Wort: Known for affecting serotonin levels, it may interact with feverfew, which also has implications for serotonin.
  • Garlic: Another supplement with blood-thinning properties, which could interact with feverfew’s effects on blood clotting.
  • Ginger: Often used for its anti-inflammatory effects, it might amplify the anti-inflammatory effects of feverfew.
  • Turmeric: Has blood-thinning and anti-inflammatory properties that may interact with similar effects in feverfew.
  • Vitamin E: Being an antioxidant and having mild blood-thinning properties, it may interact with feverfew.
  • Fish Oil: Known for its omega-3 fatty acids and blood-thinning effects, it could interact with feverfew.

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Feverfew 400mg by NOW Foods

Feverfew is an herb that has been traditionally used by European herbalists for centuries. More modern research indicates that its main bioactive compound is parthenolide. NOW® Feverfew is standardized to 0.5% – 0.7% parthenolide per capsule.

  • Standardized Extract
  • 0.5% – 0.7% Parthenolide

Suggested Use: Take 1 capsule 1 to 2 times daily, preferably with food.

Amount Per 1 Veg Capsule Serving

Feverfew Extract … 175mg* (Tanacetum parthenium) (Aerial Parts) (min. 0.5% – 0.7% Parthenolide)     

Feverfew Powder … 150mg* (Tanacetum parthenium) (Aerial Parts)      


Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

“To Sum It Up”

Feverfew offers a variety of health benefits that make it a noteworthy addition to your wellness routine. From reducing the frequency and severity of migraines to its anti-inflammatory properties, the supplement has been praised for centuries. It can also ease menstrual cramps, reduce stress and anxiety, support skin health, help with arthritis, and enhance digestive well-being. While more research is needed to fully understand its scope, the existing evidence points to a multitude of ways feverfew can improve your health.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


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