Pain Relief Naturally: Exploring Devil’s Claw’s Anti-Inflammatory Benefits

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Along with providing information on whether Devil’s Claw’s supplements might be right for you, this article also links to Fullscript where you can buy supplements online through Fullscript’s secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

Devil’s Claw, a herb native to Africa, has sparked interest for its role in nutrition and wellness circles. Named for the claw-like shape of its fruit, this plant has been traditionally used to address a variety of health concerns. Today, nutritional supplements harnessing Devil’s Claw are valued for their possible benefits, which include soothing joint pain and reducing inflammation.

And Devil’s Claw supplements are right for you, this article will show you the best place to buy Devil’s Claw online. This article describes the properties of Devil’s Claw, exploring the scientific backing behind their use and how they might contribute to a holistic approach to health.

What Is Devil’s Claw?

“Devil’s Claw, scientifically known as Harpagophytum procumbens, is an herbal remedy with a rich history in traditional medicine. Native to the arid regions of southern Africa, this plant has been valued for generations for its potential health benefits. The name ‘Devil’s Claw’ comes from the small, hook-like projections on its fruit. In traditional medicine, Devil’s Claw has been appreciated for its anti-inflammatory properties, making it a natural choice for addressing conditions related to joint discomfort and rheumatism. Let’s explore Devil’s Claw and its potential advantages for health and wellness.”

Devil’s Claw

What Are the Benefits of Devil’s Claw?

  • Natural Pain Relief: Devil’s Claw is known for its analgesic (pain-relieving) properties and is often used to alleviate various types of pain, including joint pain, arthritis, and muscle discomfort. [PMID: 17212570]
  • Anti-Inflammatory: It has anti-inflammatory effects, which can help reduce inflammation associated with conditions like osteoarthritis and rheumatoid arthritis. [PMC9182060]
  • Anti-Rheumatic Properties: It is often used in traditional herbal medicine to address rheumatic conditions, including rheumatoid arthritis. [PMID: 17886223]
  • Improved Mobility: Regular use of Devil’s Claw may enhance joint mobility and flexibility, making it easier for individuals with joint conditions to move comfortably. [PMID: 17128436]
  • Antioxidant Properties: It contains compounds with antioxidant properties, which can help protect cells from oxidative stress and damage. [PMC9182060]
  • Potential Weight Management: Some animal research suggests that Devil’s Claw may aid in weight management by acting on ghrelin receptors to reduce hunger and promote a feeling of fullness. [PMC4113378]
  • Traditional Medicine:
    • Pain and Fever: It has a history of use in traditional African medicine for various ailments, including pain and fever relief.
    • Headache Relief: Some people find relief from tension headaches and migraines when using Devil’s Claw supplements.
    • Skin Conditions: Topical application of Devil’s Claw extracts may assist in managing certain skin conditions. [PMID: 17128436]
    • Digestive Aid: Devil’s Claw has been traditionally used to support digestive health, helping with issues like indigestion and upset stomach. [PMID: 31273865]

Arthritis and other rheumatic conditions (AORC) are the leading cause of disability, are associated with poor quality of life and incur considerable direct and indirect costs…. There were statistically significant (p < 0.0001) improvements in patient assessment of global pain, stiffness and function. There were also statistically significant reductions in mean pain scores for hand, wrist, elbow, shoulder, hip, knee and back pain…. and 60% patients either reduced or stopped concomitant pain medication. Harpagophytum is an effective and well-tolerated serious treatment option for mild to moderate degenerative rheumatic disorders providing improved quality of life measure.

Effectiveness and safety of Devil’s Claw tablets in patients with general rheumatic disorders [PMID: 17886223]

Is Devil’s Claw Safe?

Devil’s Claw, known for its potential health benefits, is generally considered safe for many individuals when used as directed. It has a long history of traditional use, primarily in African and European herbal medicine, with relatively few reported adverse effects. Additionally, numerous studies and clinical trials have not raised significant safety concerns when Devil’s Claw supplements are consumed within recommended dosages. However, as with any herbal supplement or remedy, individual responses can vary, and some people may experience mild gastrointestinal discomfort or allergic reactions.

Medication Interactions with Devil’s Claw

  • Anticoagulants (Blood Thinners): Devil’s Claw may increase the risk of bleeding when taken with anticoagulant medications, potentially leading to excessive bleeding or bruising.
  • Antiplatelet Drugs: Similar to anticoagulants, Devil’s Claw may enhance the effects of antiplatelet drugs, increasing the risk of bleeding.
  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Devil’s Claw has anti-inflammatory properties, and when combined with NSAIDs, it may enhance the anti-inflammatory effects. However, this interaction could potentially increase the risk of gastrointestinal irritation and bleeding.
  • Acetaminophen (Paracetamol): Devil’s Claw may have additive analgesic (pain-relieving) effects when used with acetaminophen. This interaction might lead to more potent pain relief.
  • Antihypertensive Medications: Devil’s Claw could potentially lower blood pressure. When taken with antihypertensive medications, it may enhance their blood pressure-lowering effects, possibly causing excessively low blood pressure.
  • Diabetes Medications: Devil’s Claw may influence blood sugar levels. When combined with diabetes medications, it may lead to hypoglycemia (low blood sugar). Monitoring blood sugar levels is essential in such cases.
  • Lithium: Devil’s Claw may reduce the excretion of lithium from the body, potentially leading to increased lithium levels and an increased risk of lithium toxicity.

Supplement Interactions with Devil’s Claw

  • Blood-Thinning Supplements (e.g., Fish Oil, Ginkgo Biloba): Devil’s Claw may have mild blood-thinning properties. When taken with supplements that also have blood-thinning effects, such as fish oil or ginkgo biloba, there is a potential risk of increased bleeding or bruising.
  • Anti-Inflammatory Supplements (e.g., Turmeric, Bromelain): Devil’s Claw possesses anti-inflammatory properties. When combined with other anti-inflammatory supplements like turmeric or bromelain, it may enhance the overall anti-inflammatory effects. However, this interaction could potentially increase the risk of gastrointestinal irritation or bleeding.
  • Supplements with Hypotensive Effects (e.g., Garlic, Hawthorn): Devil’s Claw may have a mild hypotensive (blood pressure-lowering) effect. When used alongside supplements with similar effects, such as garlic or hawthorn, it may lead to excessively low blood pressure.
  • Glucose-Lowering Supplements (e.g., Berberine, Cinnamon): Devil’s Claw may influence blood sugar levels. When combined with glucose-lowering supplements like berberine or cinnamon, it could potentially lead to hypoglycemia (low blood sugar). Monitoring blood sugar levels is essential in such cases.
  • Supplements with Potential Diuretic Effects (e.g., Dandelion Root, Green Tea Extract): Devil’s Claw may have mild diuretic properties. When taken with supplements that also have diuretic effects, such as dandelion root or green tea extract, it may lead to increased urine production and potential dehydration if not managed properly.

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Devil’s Claw Secondary Root by Nature’s Way

Devil’s Claw Secondary Root

Devil’s Claw is a traditional African medicine.

Suggested Use: Take 2 capsules twice daily. If pregnant, nursing or taking any medications, consult a healthcare professional before use.

Serving Size: 2 Veg Capsules

Devil’s Claw 960 mg (tuber)

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

“To Sum It Up”

Based on traditional medicinal practices and preliminary animal research, Devil’s Claw supplements appear to offer potential health advantages. These potential benefits encompass enhanced joint health, reduced inflammation, and anti-rheumatic properties. These positive effects can be traced back to Devil’s Claw’s bioactive compounds and its longstanding use in herbal medicine traditions.

This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.

About the Author

Stephanie Figon, MS, RDN, LD

Creator of Supplement Sciences and NutriScape.NET. As a dietitian since 1992, Steph has had experiences in consulting, 15 years in clinical, and has operated a private practice nutrition counseling office for since 2011. Log in to comment and save this article on your board or send your comments to

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