Citicoline: A Natural Supplement To Fight Declining Brain Function

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Along with providing information on whether Citicoline supplements might be right for you, this article also links to Fullscript where you can buy supplements online through Fullscript’s secure healthcare formulary and get free shipping and 20% off the retail price of professional-grade supplements.

Citicoline, a naturally occurring brain chemical, has emerged as a potent dietary supplement with numerous cognitive benefits. Often heralded for its ability to enhance memory and cognitive function, citicoline plays a vital role in the synthesis of phospholipids, essential components of brain cell membranes, and neurotransmitter function. This supplement has attracted attention for its potential to improve focus, mental energy, and neuroprotective capabilities. Its use range from improving cognitive performance in healthy people to supporting recovery in traumatic brain injury, Alzheimer’s, and ADHD.

And if Citicoline supplements are right for you, this article will show you the best place to buy Citicoline online. The growing body of research on citicoline points to its role in supporting and enhancing brain health. This makes citicoline supplements interesting to anyone looking to boost cognitive function and overall brain wellness.

What Is Citicoline?

Citicoline, also known as cytidine diphosphate-choline (CDP-choline), is a naturally occurring compound found in the human brain and other tissues. It is composed of cytidine and choline, which are precursors to two important neurotransmitters, uridine and acetylcholine.

Citicoline is involved in a number of important physiological processes, including the synthesis of phosphatidylcholine, a key component of cell membranes, and the regulation of neurotransmitter levels in the brain. It has been studied for its potential health benefits, particularly in the areas of cognitive function and neurological disorders such as stroke and traumatic brain injury.

Citicoline is available as a dietary supplement in many countries, and is sometimes prescribed by healthcare providers for medical conditions.

What Are The Health Benefits of Citicoline?

Citicoline is a naturally occurring compound that is found in the human brain and other tissues. It has been the subject of numerous studies, and some potential health benefits have been identified. Here are some of the health benefits of citicoline that have been cited in research:

  • Cognitive Function: Citicoline has been shown to improve cognitive function in both healthy individuals and those with cognitive impairment. It may enhance attention, memory, and executive function. [PMC7601330]
  • Stroke Recovery: Citicoline has been studied for its potential to improve recovery after a stroke. Some studies suggest that it may help reduce the severity of symptoms and improve functional outcomes. [PMC9340348] [PMC4061873]
  • Traumatic Brain Injury: Citicoline may also have a role in treating traumatic brain injury. Research has shown that it may help reduce the extent of brain damage and improve outcomes. [PMC9958735] [PMC8146347]
  • Glaucoma: Citicoline may have a beneficial effect on eye health. Some studies suggest that it may help reduce the progression of glaucoma, a condition that can lead to blindness.
  • ADHD: Citicoline may also have a role in treating attention deficit hyperactivity disorder (ADHD). Some studies have shown that it may improve symptoms such as inattention, hyperactivity, and impulsivity. [PMID: 26179181] [PMC4517431][PMC7878037]
  • Addiction: Citicoline has been studied for its potential to reduce cravings and withdrawal symptoms in people with substance use disorders. [PMC4139283]
  • Age-related Cognitive Decline: Citicoline may have a protective effect on the brain as it ages. Some studies suggest that it may help reduce the risk of cognitive decline in older adults. [PMID: 32538854] [PMC9866349]

It is important to note that more research is needed to fully understand the potential health benefits of citicoline and to determine the optimal dosages and duration of treatment.

Medication Interactions with Citicoline

  • Blood Thinners: Citicoline might not get along well with blood-thinning medications like warfarin. Combining them could increase the risk of bleeding or bruising.
  • Stimulant Medications: Be cautious with medications that stimulate your nervous system, like ADHD medications. Mixing Citicoline with these meds might make you feel extra jittery or have trouble sleeping.
  • Antidepressants: Some antidepressants, particularly those that affect acetylcholine levels, may not work well with Citicoline. This combo could reduce the benefits of both medications.
  • Blood Pressure Medications: If you’re taking meds for blood pressure, be careful with Citicoline. It could interfere with how these medications work, making it harder to manage your blood pressure levels.
  • Cholinesterase Inhibitors: Citicoline might interact with cholinesterase inhibitors, which are used to treat Alzheimer’s disease. This combo might cause too much choline in your body, leading to side effects like digestive issues or body odor.

Supplement Interactions with Citicoline

  • Stimulants: Citicoline may not play well with stimulants like caffeine or energy supplements. Mixing these could lead to an overly excited nervous system, causing symptoms like jitteriness or trouble sleeping.
  • Blood Thinners: If you’re taking supplements that help thin your blood, like fish oil, be careful with Citicoline. The combo might increase the risk of bleeding or bruising.
  • Choline Containing Supplements: Citicoline already has choline in it, so taking it with other choline-based supplements might be too much. This could lead to side effects like digestive issues, fishy body odor, or even increased sweating.
  • Antidepressants: Some antidepressants might not mix well with Citicoline. They could end up working against each other, reducing the benefits of both supplements.
  • Blood Pressure Supplements: Be cautious if you’re taking supplements that help with blood pressure. Citicoline might interfere with how they work, making it harder to manage your blood pressure levels.

Order Citicoline Online

Why Professionals Choose the Fullscript Formulary

Your health is on the line. Health professionals know that many other online and retail options set a very low bar for quality–sometimes amazingly low. The Fullscript formulary is the most secure online source for the highest quality brands securely sourced to assure freshness and purity. Here’s what makes Fullscript the best:

  • Meticulous vetting of brand quality. Health professionals trust Fullscript to continuously monitor the quality of each item on the platform. Other retailers operate with profit as their highest or only motive when choosing brands. Fullscript cares only about quality and reliability. Unlike discount stores, large online marketplaces, and other retailers you won’t find ingredients sourced from China or other questionable locations or companies.
  • Always 20% Discount off the manufacturer’s retail price. When you follow any link from Supplement-Sciences.com, you will automatically get 20% off the retail price.
  • Free shipping over $50.
  • Freshness. Fullscript prioritizes freshness over bulk buying even if it means an increased risk of briefly being out of stock.
  • Top quality phone and online support. When you call, knowledgeable humans at Fullscript answer your questions.
  • How It Works:
    • Easy Sign-up & No Spam Email: Click the “View Product” button below to be taken to Fullscript’s login page where you can quickly create your secure account with just your name, email, and phone number. Then you will be taken directly to the product page.
    • Wide variety of supplement options: Once you sign in to your account, you are not limited to the products listed below. You will see similar items listed at the bottom of each product page on Fullscript.
    • Search For What You Want: Once inside Fullscript, you can search for the exact brands and products you want from their wide selection of quality brands.

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CDP Choline 250mg by Jarrow Formulas

Citicoline [stabilized CDP Choline (cytidine 5’-diphosphocholine)] is a naturally occurring intermediate involved in the synthesis of phosphatidylcholine, a major constituent of the grey matter of brain tissue (30%).* Citicoline consumption promotes brain metabolism by enhancing the synthesis of acetylcholine and restoring phospholipid content in the brain, both of which positively affect memory and other brain activity.*
Take 1 capsule up to 2 times per day with food or as directed by your qualified healthcare professional.

Amount Per 1 Capsule Serving
Citicoline … 250mg
(Cognizin®)(from Stabilized Cytidine 5′-Diphosphocholine)


Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

To Sum It Up

Citicoline supplements present a promising option for those looking to support cognitive health and brain function. As a natural compound that plays a key role in the synthesis of phospholipids and neurotransmitters, citicoline has demonstrated potential benefits in enhancing memory, improving focus, and supporting overall brain health. Its use in conditions like cognitive impairment, memory disorders, and even in the recovery from stroke highlights its therapeutic value. While more research is needed to fully understand the extent of its benefits and optimal dosing, current evidence suggests that citicoline could be a valuable addition to a cognitive health regimen. Whether you’re seeking to boost your cognitive capabilities, support brain health as you age, or recover from neurological impairments, citicoline supplements offer a compelling avenue worth considering, backed by scientific research and clinical studies.


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


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