ACE Inhibitor Interactions: Zinc Depletion Is An Issue

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Along with providing information on whether Zinc supplements might be right for you, this article also links to Fullscript where you can buy high quality supplements. Order online through Fullscript’s secure healthcare formulary to get the best prices and free shipping on professional-grade supplements.

The following is a list of the ACE inhibitors that are available in the US:

  • benazepril (Lotensin)
  • captopril (Capoten- discontinued brand)
  • enalapril (Vasotec, Epaned, [Lexxel- discontinued brand])
  • fosinopril (Monopril- Discontinued brand)
  • lisinopril (Prinivil, Zestril, Qbrelis)
  • moexipril (Univasc- Discontinued brand)
  • perindopril (Aceon)
  • quinapril (Accupril)
  • ramipril (Altace)
  • trandolapril (Mavik)

Drug-Induced Nutrient Depletions

  • ZincACE inhibitors deplete zinc. [PMC5874849] If you take any of the ACE inhibitors, your multivitamin should include 11mg of Zinc. [PMID: 16819574]

Interactions

  • Potassium: DO NOT USE POTASSIUM-BASED SALT SUBSTITUTES. ACE inhibitors can reduce potassium clearance by the kidneys.  This can cause excessive potassium to build up in the blood and can lead to irregular heartbeat when very high levels of potassium are consumed. Don’t use potassium supplements (or electrolyte drinks) without your physician’s approval.  
  • CoQ10 and Fish Oil can reduce blood pressure. If you are taking blood pressure medicines, be careful to monitor blood pressure when adding CoQ10 or Fish Oil.
  • Garlic, Ginkgo

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Order Supplements To Replace Zinc

Why Professionals Choose the Fullscript Formulary

Your health is on the line. Health professionals know that many other online and retail options set a very low bar for quality–sometimes amazingly low. The Fullscript formulary is the most secure online source for the highest quality brands securely sourced to assure freshness and purity. Here’s what makes Fullscript the best:

  • Meticulous vetting of brand quality. Health professionals trust Fullscript to continuously monitor the quality of each item on the platform. Other retailers operate with profit as their highest or only motive when choosing brands. Fullscript cares only about quality and reliability. Unlike discount stores, large online marketplaces, and other retailers you won’t find ingredients sourced from China or other questionable locations or companies.
  • Free shipping over $50 and best prices when you order through Supplement Sciences.
  • Freshness. Fullscript prioritizes freshness over bulk buying even if it means an increased risk of briefly being out of stock.
  • Top quality phone and online support. When you call, knowledgeable humans at Fullscript answer your questions.
  • How It Works:
    • Easy Sign-up & No Spam Email: Click the “View Product” button below to be taken to Fullscript’s login page where you can quickly create your secure account with just your name, email, and phone number. Then you will be taken directly to the product page.
    • Wide variety of supplement options: Once you sign in to your account, you are not limited to the products listed below. You will see similar items listed at the bottom of each product page on Fullscript.
    • Search For What You Want: Once inside Fullscript, you can search for the exact brands and products you want from their wide selection of quality brands.

O.N.E. Multivitamin — Pure Encapsulations

Serving Size: 1 capsule / Dose: 1 per day

Amount Per Serving
Vitamin A … 1,125mcg (as vitamin A acetate and 73% beta carotene)
Vitamin C … 180mg (as ascorbic acid)
Vitamin D … 50mcg (as cholecalciferol) (D3) (2,000 IU)
Vitamin E … 20mg (as d-alpha tocopherol succinate)
Thiamin … 3mg (as thiamin HCl) (B1)
Riboflavin … 3mg (as vitamin B2 and 43% riboflavin 5′ phosphate (activated B2))
Niacin … 20mg (as niacinamide)
Vitamin B6 … 4mg (as pyridoxine HCl and 38% pyridoxal 5′ phosphate (activated B6))
Folate … 667mcg DFE (as Metafolin®, L-5-MTHF) (L-5-MTHF 400 mcg)
Vitamin B12 … 500mcg (as methylcobalamin)
Biotin … 300mcg
Pantothenic acid … 10mg (as calcium pantothenate) (B5)
Iodine … 150mcg (as potassium iodide)
Zinc … 25mg (as zinc citrate)
Selenium … 70mcg (as selenomethionine)
Manganese … 2mg (as manganese citrate)
Chromium … 200mcg (as chromium polynicotinate)
Molybdenum … 75mcg (as TRAACS™ molybdenum glycinate chelate)
Boron … 1mg (as boron glycinate)
Choline … 10mg (as choline bitartrate)
Inositol … 25mg
Coenzyme Q10 sustained-release … 50mg (as CoQ10 and as 18% from MicroActive® CoQ10-cyclodextrin complex)
Alpha lipoic acid … 50mg
FloraGLO® lutein … 3mg
Zeaxanthin … 500mcg
Lycopene … 500mcg

Food First!

Although this article discusses supplements in detail, don’t forget that we are absolutely committed to the “Food First” approach to nutrition. When it comes to your health, the totality of your eating habits far surpasses the impact of individual nutrients or any single supplement you consume. Even though this article doesn’t delve into the broader picture of your overall diet, it’s crucial to keep this element at the forefront of our minds. Your food needs to provide all the vitamins, minerals, fiber, and phytochemicals to nourish your body systems down to the cellular level.

Food choices, rather than supplements, are the most critical factors for a healthy gut microbiome. These trillions of tiny inhabitants in your gut affect your brain waves; they orchestrate your immune system. They possess the power to create molecules that can switch genes on or off and are even capable of synthesizing neurotransmitters. Opting for organic foods and steering clear of plastic packaging (including those labeled BPA-free) is a smart move to limit toxin exposure. The sum of all these parts leads to a powerful conclusion: the ultimate key to your health lies in the quality and balance of the food you consume. Supplements are secondary.

What To Eat


This Article is Not a Substitute for Medical Advice

Dietary supplements are not designed to diagnose, treat, cure, or prevent any disease. The Supplement Sciences website seeks to provide comprehensive access to the most relevant supplement information along with convenient online ordering. We do not provide medical advice and cannot guarantee that every product suggested is completely without risk. Since each person is unique in their health history and medication use, it is important to discuss supplements with your personal physician. Specifically, pregnant women and individuals being treated for cancer or liver or kidney problems must consult their physician about every nutritional supplement they plan to take. People taking medications for the treatment of HIV or with a history of organ transplant must not take supplements without consulting with their physician.


About the Author

Stephanie Figon, MS, RDN, LD

Creator of Supplement Sciences and NutriScape.NET. As a dietitian since 1992, Steph has had experiences in consulting, 15 years in clinical, and has operated a private practice nutrition counseling office for since 2011. Log in to comment and save this article on your board or send your comments to reviews@supplement-sciences.com

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